DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Wdr92 and CG12782

DIOPT Version :9

Sequence 1:	NP_649025.1	Gene:	Wdr92 / 39997	FlyBaseID:	FBgn0036771	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_611772.2	Gene:	CG12782 / 37685	FlyBaseID:	FBgn0034838	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	66/323 - (20%)
Similarity:	102/323 - (31%)	Gaps:	126/323 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 QVLDMEQPDLPVYNVKAHNGIINTIDAIGGTQIDCGAPEIVTGSRDGAVKVWDIRQGQAPVVDMS 154
            |..|.|.|:.|          .:||.|:..:........|..||.|..|::|:::      .|..
  Fly    11 QQQDYELPNPP----------NDTISALEFSPRSSSWNAICAGSWDNTVRIWEVQ------ADRL 59

  Fly   155 PPPQMGDGVNNSSGRRDCWAVAFGNTYNAEERIVAAGYDNGDLKIFDLRSLSVR----------- 208
            .|..|    |:..|      ..|..|:|.....|.....:|.:..:||.|..:|
  Fly    60 VPKVM----NSLEG------TPFDVTWNDSGNKVYLSDSSGQVTEWDLESNQLRKVGLHARAART 114

  Fly   209 ------------WEATMK--NGICGLEFDRRDIP--------MNKLAVT----------TLEGGL 241
                        |:.:::  :....:|..|.::|        :|.:||.          ||.||
  Fly   115 CHWVGPYLATTSWDKSIRFWDPRAAIELTRMELPDRSYAADVLNDVAVVACGDRSILAYTLRGG- 178

  Fly   242 LVFDMRTQHPTKGFSYVEERNAGRSVGTNGVISGPKATVWVVRHLPQNRDLFLTGGGTGSIRLWQ 306
            .|...|.:.|.:..:.|      |||.                 |.|||||          ..|.
  Fly   179 PVEQGRMKSPGESNTQV------RSVA-----------------LHQNRDL----------TSWL 210

  Fly   307 YEYPDRRVIDDSDGNKL-------------GVAGA-------LNMLS--AATLSSQPVHCFDW 347
            ....:..|.|.|..::.             |:...       :||::  .||:.|..|.|| |
  Fly   211 IAKTNGMVFDQSMAHRTVSFPIRCHRRENSGILDVYAVNEVKVNMVTQHIATVGSDGVFCF-W 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr92	NP_649025.1	WD40	<2..354	CDD:225201	66/323 (20%)
		WD40	77..366	CDD:295369	66/323 (20%)
		WD40 repeat	111..165	CDD:293791	12/53 (23%)
		WD40 repeat	173..210	CDD:293791	9/59 (15%)
		WD40 repeat	217..256	CDD:293791	13/56 (23%)
		WD40 repeat	280..333	CDD:293791	13/72 (18%)
		WD40 repeat	342..366	CDD:293791	4/6 (67%)
CG12782	NP_611772.2	WD40	<19..303	CDD:225201	62/315 (20%)
		WD40	25..303	CDD:295369	60/299 (20%)
		WD40 repeat	26..64	CDD:293791	9/43 (21%)
		WD40 repeat	71..101	CDD:293791	8/29 (28%)
		WD40 repeat	109..146	CDD:293791	3/36 (8%)
		WD40 repeat	195..235	CDD:293791	14/72 (19%)
		WD40 repeat	242..272	CDD:293791	8/30 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447784
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10971
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030