Protein Alignment Prestin and YPR003C

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_015328.1
• Gene: YPR003C / 856111
• SGDID: S000006207
• Length: 754
• Species: Saccharomyces cerevisiae
• Alignment Length: 743
• Identity: 155/743 - (20%)
• Similarity: 274/743 - (36%)
• Gaps: 178/743 - (23%)

  Fly     2 PSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIPSSLRN 66
            |::..|..|...||.|...|..:           :.:.|.:....|.:...|
Yeast    63 PNNSRSGCTNNTNNTNNTSNTSN-----------TNNNDSVDENTVFETLPY------------- 103

  Fly    67 CWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGI-LAGVSAGNGLY 130
                         .:|...|||:|:..: |.||:|||.:||...||..::|.. :|.|....|||
Yeast   104 -------------YLPCFSWLPEYTFNK-LWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLY 154

  Fly   131 MAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPL 195
            ........|..||:...:.:|..:..|::..:.|::.
Yeast   155 SLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESI---------------------------- 191

  Fly   196 LLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLS 260
                                     ||:.:.::.|:::|.:....|.:.|.....|.|.|.::||
Yeast   192 -------------------------TLHKENVSLIDISTVITFVSGTILLFSGISRFGFLGNVLS 231

  Fly   261 EPLVNGFTTAAACHVV----TAQLK-DVLGISVPRH-KGAFKIIYTVIDVIKGVPQTNLVNFGFC 319
            :.|:.||.::....::    .::|| |...:|:|:| ...|:.|..:||............|..|
Yeast   232 KALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGC 296

  Fly   320 MAVIAFMMICNEILKPRLSK--KCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIP----S 378
            ..::.|:   ..:||.:|.|  |.....|..|::||...|||..|||...|.::.:|...    .
Yeast   297 CLIVLFL---TRLLKRKLMKYHKSAIFFPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFD 358

  Fly   379 GLPEPVL-PRLDLVPKVAVDSIAIAIVTY----SIIMSMGLTFAKKHGYEVRPNQELFAMGIGNM 438
            .|..|:. ||..|:|.:...|:.:|::.:    :...|:|.|:    ...|..|:||.|:|..|:
Yeast   359 ELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTY----NLTVSSNRELVALGFMNI 419

  Fly   439 VGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVAL 503
            |...|..:|......||.|...:|..|.::.:....:.::|:..:..|...:|.|||:.:..:..
Yeast   420 VISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIG 484

  Fly   504 KPMFMQAKELKKFSKQ--GKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALY----------- 555
            ..:..:.....||..:  |..|:|.:..||...:...|:.|:.||...|::.:.
Yeast   485 ISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQIL 549

  Fly   556 --IKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQV---PEVR---IFRYSGSLNFATSLFFRRAL 612
              :.|...::.|..||         :|..||::.|   .|:.   |.|....|.|..|...::.|
Yeast   550 ARVAGTSNFTNLDDYM---------MNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRL 605

  Fly   613 --YEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLG 675
              .|..|..||                         ..|.|::..|     .:.|.::.|...:.
Yeast   606 DRIERYGSSKI-------------------------HPGRKSLRSK-----DSIKYVIFDLGGMT 640

  Fly   676 HIDVAGCRTLTDLSKELKVRGARLLLAS 703
            .||.:..:.|.::....|.|...:.|.:
Yeast   641 SIDSSAAQVLEEIITSYKRRNVFIYLVN 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	145/663 (22%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	25/130 (19%)
YPR003C	NP_015328.1	SUL1	99..732	CDD:223732	146/696 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.780