DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prestin and SULTR2;1

DIOPT Version :9

Sequence 1:	NP_649024.1	Gene:	Prestin / 39996	FlyBaseID:	FBgn0036770	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_196580.1	Gene:	SULTR2;1 / 830882	AraportID:	AT5G10180	Length:	677	Species:	Arabidopsis thaliana

Alignment Length:	792	Identity:	190/792 - (23%)
Similarity:	302/792 - (38%)	Gaps:	180/792 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DKESPET-----KPLNNNNTN------GNGGS-------------------VPSKPKIQPKYSIH 38
            |.||.|:     .|..:|:|:      .|.||                   .|..|  .|.:.:.
plant     5 DSESFESLSHQVLPNTSNSTHMIQMAMANSGSSAAAQAGQDQPDRSKWLLDCPEPP--SPWHELK 67

  Fly    39 RDV----LTHEVVIKQTGYAARDKSIPSSLRNCWRSWNFFALFTGVIPILQWLPQYSPRRDLPGD 99
            |.|    ||.....|........|.|.|.|:             .:.||..|...|.... ...|
plant    68 RQVKGSFLTKAKKFKSLQKQPFPKQILSVLQ-------------AIFPIFGWCRNYKLTM-FKND 118

  Fly   100 IIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVV 164
            ::||.|:|.:.||..:.|..||.:....|||.:|.|.|.|..:|||:.|:||..||.|:
plant   119 LMAGLTLASLCIPQSIGYATLAKLDPQYGLYTSVVPPLIYALMGTSREIAIGPVAVVSL------ 177

  Fly   165 DTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITK 229
                                                  |..|:....|.|        ..||:..
plant   178 --------------------------------------LISSMLQKLIDP--------ETDPLGY 196

  Fly   230 IEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGA 294
            .::..:.....||........|||.|...||...:.||...||..:...|||.:|||:      .
plant   197 KKLVLTTTFFAGIFQASFGLFRLGFLVDFLSHAAIVGFMGGAAIVIGLQQLKGLLGIT------N 255

  Fly   295 FKIIYTVIDVIKGV---------PQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELI 350
            |.....::.|::.|         |.|.::...|    ::|::|...|.| :..|....|..|.||
plant   256 FTTNTDIVSVLRAVWRSCQQQWSPHTFILGCSF----LSFILITRFIGK-KYKKLFWLPAIAPLI 315

  Fly   351 MVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDL----VPKVAVDSIAIAIVTYSIIMS 411
            .|:..||: .:.....::.|..|..|..||....:..||.    :.::|...:.||||..:..::
plant   316 AVVVSTLM-VFLTKADEHGVKTVRHIKGGLNPMSIQDLDFNTPHLGQIAKIGLIIAIVALTEAIA 379

  Fly   412 MGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLV 476
            :|.:||...||.:..|:|:.|:|..|::|...||.....|.||:.:....|..:.::::|.|..|
plant   380 VGRSFAGIKGYRLDGNKEMVAIGFMNVLGSFTSCYAATGSFSRTAVNFAAGCETAMSNIVMAVTV 444

  Fly   477 VVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDI 541
            .|.|..:.......|..:||.:|:.|| |..:...|.....|..|.:....|..|..|:...::|
plant   445 FVALECLTRLLYYTPIAILASIILSAL-PGLININEAIHIWKVDKFDFLALIGAFFGVLFASVEI 508

  Fly   542 GLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRY-SGSLNFATS 605
            |||:.:.||...:.:..::|....||.|| ....:.|.||:...::.|.|.|||. |..|.||.:
plant   509 GLLVAVVISFAKIILISIRPGIETLGRMP-GTDTFTDTNQYPMTVKTPGVLIFRVKSALLCFANA 572

  Fly   606 LFFRRALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVL--V 668
            ......:...|..::      ...|:.|.:|.                           |:|  |
plant   573 SSIEERIMGWVDEEE------EEENTKSNAKR---------------------------KILFVV 604

  Fly   669 LDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSEGPF------EIFP 727
            ||.|.|.::|.:|...|.:|..:|...|..|::.:|..:|    :|.  |::..|      :::.
plant   605 LDMSSLINVDTSGITALLELHNKLIKTGVELVIVNPKWQV----IHK--LNQAKFVDRIGGKVYL 663

  Fly   728 TLHDCVEYANAC 739
            |:.:.::   ||
plant   664 TIGEALD---AC 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	166/670 (25%)
Prestin	NP_649024.1	STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	33/156 (21%)
SULTR2;1	NP_196580.1	sulP	102..668	CDD:273284	166/671 (25%)
SULTR2;1	NP_196580.1	STAS	548..668	CDD:279997	33/158 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.780