DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prestin and SULTR3;4

DIOPT Version :9

Sequence 1:	NP_649024.1	Gene:	Prestin / 39996	FlyBaseID:	FBgn0036770	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_188220.1	Gene:	SULTR3;4 / 820844	AraportID:	AT3G15990	Length:	653	Species:	Arabidopsis thaliana

Alignment Length:	751	Identity:	189/751 - (25%)
Similarity:	317/751 - (42%)	Gaps:	165/751 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVI--KQTGYAARDKSI-----P 61
            |..||      ||.|.|                 ...|..|.|.:  |:|.:....|.:     |
plant    10 DMASP------NNGTAG-----------------ETVVEIHSVCLPPKKTAFQKLKKRVGDVFFP 51

  Fly    62 SS----LRN-CWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILA 121
            ..    .|| .||:.....| ..:.||..|..||..:. |..|:|:|.|:|.:.||.|::|..||
plant    52 DDPLQRFRNQTWRNRVILGL-QSLFPIFTWGSQYDLKL-LRSDVISGLTIASLAIPQGISYAKLA 114

  Fly   122 GVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQS 186
            .:....|||.:..|.|.|..||:|:|:::|..::||
plant   115 NLPPIVGLYSSFVPPLIYAVLGSSRHLAVGPVSIAS----------------------------- 150

  Fly   187 NGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLR 251
                      |:..|.|::|||.|             .|.|..:::|.:.....|:....:..||
plant   151 ----------LVMGSMLSESVSPT-------------QDSILYLKLAFTSTFFAGVFQASLGLLR 192

  Fly   252 LGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVP----QTN 312
            ||.:...||:..:.|||..||..|...|||.:|||  ....|..:|:..:..|.....    :|.
plant   193 LGFMIDFLSKATLIGFTAGAAVIVSLQQLKGLLGI--VHFTGKMQIVPVMSSVFNHRSEWSWETI 255

  Fly   313 LVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPA--ELIMVIGGTLISKWFNLYV----DYNVN 371
            ::..||...::....|  .:.||:|     |.:.|  .|..||..||:     :|:    .:.::
plant   256 VMGIGFLSILLTTRHI--SMRKPKL-----FWISAASPLASVIISTLL-----VYLIRSKTHAIS 308

  Fly   372 PVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVTYSI--IMSM------GLTFAKKHGYEVRPNQ 428
            .:|.:|.||..|.|..|    ..:...:|:||.|..|  |:|:      |.|||....|:|..|:
plant   309 FIGHLPKGLNPPSLNML----YFSGAHLALAIKTGIITGILSLTEGIAVGRTFASLKNYQVNGNK 369

  Fly   429 ELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRC 493
            |:.|:|..||.|.|.||.....|.|||.:....|..:.::::|.||.|:|||:::.|.|...|..
plant   370 EMMAIGFMNMAGSCTSCYVTTGSFSRSAVNYNAGAKTAVSNIVMASAVLVTLLFLMPLFYYTPNV 434

  Fly   494 VLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKG 558
            :||.:|:.|:..: :..:...|..|..|.:.||.:.:|..|:.:.:.:||.|.:.:|::.:.:..
plant   435 ILAAIILTAVIGL-IDYQAAYKLWKVDKFDFFTCLCSFFGVLFVSVPLGLAIAVAVSVIKILLHV 498

  Fly   559 LKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPL 623
            .:|.:...|.:| ...||..|.::|.|.::|...|......:.||.|.:.:         |:|
plant   499 TRPNTSEFGNIP-GTQIYQSLGRYREASRIPGFLILAIESPIYFANSTYLQ---------DRI-- 551

  Fly   624 TKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDL 688
                       .:.::...:.:.:|.|..:           |.::||.:.:..||.:|...:.:|
plant   552 -----------LRWAREEENRIKENNGTTL-----------KCIILDMTAVSAIDTSGLEAVFEL 594

  Fly   689 SKELKVRGARLLLASPVDRVYDTL-----VHSMALS 719
            .:.|:.:..:|:|.:||..|.:.|     :.::.||
plant   595 RRRLEKQSLQLVLVNPVGTVMEKLHKSKIIEALGLS 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	170/661 (26%)
Prestin	NP_649024.1	STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	27/143 (19%)
SULTR3;4	NP_188220.1	sulP	76..639	CDD:273284	170/661 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D690428at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.790