Protein Alignment Prestin and CG7912

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_651761.2
• Gene: CG7912 / 43561
• FlyBaseID: FBgn0039736
• Length: 602
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 164/723 - (22%)
• Similarity: 280/723 - (38%)
• Gaps: 188/723 - (26%)

  Fly    59 SIPSSLRNC--WRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILA 121
            ::.|..|:|  .||.:.:      :|:..|||:|. ...|..|::||.||.:..:|..:|||.:|
  Fly    19 AVSSKARSCCSMRSVHRY------LPVTDWLPKYQ-LNFLAMDVVAGLTVGLTAVPQAIAYGAVA 76

  Fly   122 GVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQS 186
            .:....|||.|......|:.|||.|.|::|..|:.::|....||
  Fly    77 NLPPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYVD--------------------- 120

  Fly   187 NGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLR 251
             |....:.|:...|                                        |.:..||..|.
  Fly   121 -GNPAYAVLICFLS----------------------------------------GCIITLMGLLN 144

  Fly   252 LGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQT--NLV 314
            ||.|...:|.|:..|||.|||..:.|.|:..:.|||    ..|...:.:.|.....:.||  |..
  Fly   145 LGVLMRFISVPVTTGFTMAAALTIATGQVNSLFGIS----SSASGFLNSWIYFFGHITQTRRNDA 205

  Fly   315 NFGFCMAVIAFMMICNEILKPRLSKKCRF---------PLPAELIMVIGGTLISKWFNLYVDYNV 370
            ..|.|..|:..:|        |..|...|         .|....:.|:.|.|:.        |.:
  Fly   206 ILGCCTLVLLLLM--------RQLKNLTFGFKSVWKYISLARNAVAVLIGILLC--------YLL 254

  Fly   371 NPVGKIP---SGLPEPVLPRLDLVP--------------KVAVDSIAIAIVT---YSIIMSMGLT 415
            ...||:|   ||...|.||...|.|              ...|.::..|:|:   .||:.|:.:.
  Fly   255 KNDGKLPFLVSGSITPGLPPFKLPPFHTEDPETGETISFGGMVSNVGTALVSIPLLSILESIAVA 319

  Fly   416 FAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTL 480
            .|...|..|..:||:.|:|:.|::...||.:|:..|.:|:.|.:.:|..:.:...|:.:||::||
  Fly   320 KAFSKGKIVDASQEMIALGVSNILSSFFSSMPITGSFTRTAINNASGVKTPLGGAVTGALVLMTL 384

  Fly   481 MWIGPFFSSLPRCVLAGVIIVALKPMFM-QAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLL 544
            .::...|:.:|:..||.:||.|:  .|| :.:.:.:..:..|.:|..::.|.|..|...::.|::
  Fly   385 AFLTTTFAYIPKATLAAIIIAAM--FFMVEYETIGEIWRAKKRDMLPFLVTVLTCVFWTLEYGMV 447

  Fly   545 IGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFR 609
            :||..:.|.|..|.:||...|             ..:..|.:   ||.:....||:::|.:.:.:
  Fly   448 VGIVFNALFLLYKSMKPQFFL-------------TTEKFNGI---EVTMADLKGSVDYAAAEYLK 496

  Fly   610 RALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSML 674
            .:|          ::.|:..||                           |.|....::|:....:
  Fly   497 MSL----------VSHVTQRNS---------------------------EGSAPTTLVVIKGHEI 524

  Fly   675 GHIDVAGCRTLTDLSKELKVRGARLL-------LASPVDRVYDTLVHSMALSEGPF-EIFPTLHD 731
            ..||......|..|.::|.:....::       .|..:.|: |..:.||......| ::..|:.|
  Fly   525 ASIDTTVALNLKSLREDLALLKCDMICWNWSIPAAGVICRM-DRKLRSMFKFSKSFPDLMQTIAD 588

  Fly   732 CVEYANAC 739
             .|.|::|
  Fly   589 -AEAADSC 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	155/688 (23%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	25/155 (16%)
CG7912	NP_651761.2	sulP	38..542	CDD:273284	147/641 (23%)
		STAS	485..582	CDD:294402	21/134 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
	9	8.780