Protein Alignment Prestin and CG5404

DIOPT Version :10

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_650482.1
• Gene: CG5404 / 41901
• FlyBaseID: FBgn0038354
• Length: 627
• Species: Drosophila melanogaster
• Alignment Length: 655
• Identity: 141/655 - (21%)
• Similarity: 247/655 - (37%)
• Gaps: 192/655 - (29%)

  Fly    81 IPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTS 145
            :|:.||||.||....: .|.|||.|:.:..||..||..:|||:.|..||..|....|.||..|:.
  Fly    49 VPVFQWLPLYSTEWGI-DDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSI 112

  Fly   146 KHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSST 210
            ..:.||..::.:::                                              ||..|
  Fly   113 DKVIIGPTSLVALV----------------------------------------------SVQFT 131

  Fly   211 TISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHV 275
            ...|               ||.|..|....|||.::|..:|:|.:...:|.|::..|::|.|..|
  Fly   132 VGRP---------------IEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPVIKAFSSATAILV 181

  Fly   276 VTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGV-------PQTNLVNFGFCMAVIAFMMIC---- 329
            :.:|||.:|||.           |.|..::..|       .::|:.:....:..|.|:::.
  Fly   182 IESQLKVLLGIK-----------YLVAGLMNSVGMLSSRIEESNMADLIMGVCAIVFLLLLELLD 235

  Fly   330 ----NEILKPRLSKKCRFPLPAE--LIMVIGGTLISKWFNLYVDYNVNPVGKIP--------SGL 380
                ||.....|...||:...:.  ||::|...:...|        :...|::|        |.|
  Fly   236 RVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIW--------IQKCGQVPYALSKNALSTL 292

  Fly   381 PEPVLPRL------------DLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAM 433
            |...:|..            :::.::.:..|.|.||.....:|:|....|  |. |..||||..:
  Fly   293 PNFTVPSFHIETAERNYSIWEVLKELNIGIIVIPIVGILTNISIGKLTPK--GL-VDTNQELLTV 354

  Fly   434 GIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGV 498
            |:.||.|.|...:|.:.:.:|..|....|..:.:|:|....:|::.|.::.|:|:.:|...||.:
  Fly   355 GLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAI 419

  Fly   499 IIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYS 563
            :|.::..: :..|...:..:..|.:..||:..|...|:..:::||.:.|.::.|.|.....:
  Fly   420 LICSIFTL-LDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFLWAR--- 480

  Fly   564 CLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPLTKVSS 628
                                     ||:|:                    :...||::...:|:.
  Fly   481 -------------------------PEIRV--------------------KIEQLDEMQYIRVTP 500

  Fly   629 SNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGA-----FKV-LVLDFSMLGHIDVAGCRTLTD 687
            ||         ..|.|       |||...|....|     |:: :|:|...:..:|....:.::.
  Fly   501 SN---------GIYFP-------AINYLRERVLKACEQADFRITVVIDGQRISGMDYTAAQGISK 549

  Fly   688 LSKEL 692
            ||.:|
  Fly   550 LSSDL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	PRK11660	82..731	CDD:481320	141/654 (22%)
CG5404	NP_650482.1	PRK11660	50..557	CDD:481320	141/654 (22%)