Protein Alignment Prestin and slc26a11

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_956061.1
• Gene: slc26a11 / 327138
• ZFINID: ZDB-GENE-030131-5349
• Length: 572
• Species: Danio rerio
• Alignment Length: 722
• Identity: 170/722 - (23%)
• Similarity: 276/722 - (38%)
• Gaps: 236/722 - (32%)

  Fly    67 CWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYM 131
            ||     |.......||:.|||:|: ...|..|:|||.||.:..:|..:||..:||:....|||.
Zfish     6 CW-----FPALRSCFPIITWLPRYN-LTWLKMDVIAGLTVGLTAVPQALAYAEVAGLPVQYGLYS 64

  Fly   132 AVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLL 196
            |......|...||||.|::|..|:.|:
Zfish    65 AFMGGFIYCIFGTSKDITLGPTAIMSL-------------------------------------- 91

  Fly   197 LINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSE 261
                                |.:|.:..||:    .|..|.|..|::...||.||||.|...:|.
Zfish    92 --------------------LCSSYITGDPV----FAVVLTLLCGVIQTGMALLRLGFLLDFISY 132

  Fly   262 PLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYT--------VIDVIKGVPQTNLVNFGF 318
            |::.|||.|||..:...|:|::||:.....:...::.||        |.|||.|      ::..|
Zfish   133 PVIKGFTCAAAVTIGFGQVKNILGLKEIPQQFFLQVYYTFHKIPEARVGDVILG------LSCLF 191

  Fly   319 CMAVIAFMMICNEI--------LKPRLSKKCRFPLP----AELIMVIGGTLIS------KWFNLY 365
            .:.::.||.  |.:        ...|.:::..:.|.    |.:::...|...|      .:|:|
Zfish   192 FLLILTFMK--NSLNSAEDEASFLVRSARQLLWSLATIRNALVVIAAAGVAFSAEVTGNHFFSL- 253

  Fly   366 VDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAI-AIVTYS-----------IIMSMGL---- 414
                   .||...|||....|.|.       ::||. .::|:|           :|..||:
Zfish   254 -------TGKTAKGLPPFRAPPLS-------ETIANGTVITFSDIAKDLGGGLAVIPLMGVLESI 304

  Fly   415 ----TFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASL 475
                .|..|:.|.:..||||||:|:.|::|...|..|:..|..|:.:..|||..|....::::.:
Zfish   305 AIAKAFGSKNNYRIDANQELFAIGLTNIMGSFVSAYPVTGSFGRTAVNSQTGVCSPAGGIITSVI 369

  Fly   476 VVVTLMWIGPFFSSLPRCVLAGVIIVALKPM--FMQAKELKKFSKQGKLEMFTWISTFLCVVIID 538
            |:::|.::.|.|..:|:..||.|||.|:.||  |.....:.:..   :|::..::.||| :...:
Zfish   370 VLLSLAFLMPLFFYIPKASLAAVIICAVSPMVDFRVPLHIWRVK---RLDLLPFLVTFL-LSFWE 430

  Fly   539 IDIGLLIGICIS-LLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVR-------IFR 595
            :..|:..|:.:| .:.|||                             |..|:|:       :..
Zfish   431 VQYGIAGGVLVSAFMLLYI-----------------------------MARPKVKVSDHGVIVLE 466

  Fly   596 YSGSLNFATSLFFRRALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEET 660
            ....|||.::....|.:|:            .:.:::.|
Zfish   467 IDNGLNFTSTEHLSRLVYK------------HALHASPP-------------------------- 493

  Fly   661 SGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGAR-------------LLLAS-PVDRVYDT 711
                :.||||.|.:..||......||||.|:.::|||.             ||||. |..|..||
Zfish   494 ----RSLVLDCSQISSIDFTVIHELTDLLKQFQIRGAALIFTGLKPSVLQVLLLADLPAFRHTDT 554

  Fly   712 LVHSMAL 718
            :..::.|
Zfish   555 VDEALQL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	167/707 (24%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	33/158 (21%)
slc26a11	NP_956061.1	sulP	16..541	CDD:273284	158/685 (23%)
		STAS_SulP_like_sulfate_transporter	454..546	CDD:132913	26/133 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740