Protein Alignment Prestin and Slc26a7

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_038965346.1
• Gene: Slc26a7 / 297910
• RGDID: 1310846
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 184/664 - (27%)
• Similarity: 312/664 - (46%)
• Gaps: 92/664 - (13%)

  Fly    81 IPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTS 145
            :|||:|.|||:.:.:|..|.::|..:|:..:..|:::.||:.|....|||.::||.:.|...|..
  Rat    32 LPILEWAPQYNLKENLLPDTVSGVLLAVQQVTQGLSFAILSSVHPVFGLYGSLFPAIIYAIFGMG 96

  Fly   146 KHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSST 210
            :|::.||||:.|:::|..|:         :::|      |||...|...    |||.|.
  Rat    97 RHVATGTFALTSLISANAVE---------RLVP------QSNRNLTTQS----NSSVLG------ 136

  Fly   211 TISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHV 275
             :|.|:|          .:|.||.:::...|::.|:|..|:||..:.||:||:::..||.||.||
  Rat   137 -LSEFEL----------QRIGVAAAVSFLGGVIQLVMFVLQLGNATFLLTEPVISAMTTGAATHV 190

  Fly   276 VTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKK 340
            ||:|:|.:|||.:|...|.....|....|.:.:....|......:..|..:::..| |..:..:|
  Rat   191 VTSQVKYLLGIKMPYISGPLGFFYIYAYVFENIKSVQLEALLLSLLSIVVLVLVKE-LNEQFKRK 254

  Fly   341 CRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVT 405
            .:..||.:|:::|..:......|:...|.:..||:||.|:|.|..|.::::..|..::..:|:|.
  Rat   255 IKVVLPVDLVLIIAASFACYCTNMENTYGLEVVGRIPKGIPPPRAPPMNILSAVLTEAFGVALVG 319

  Fly   406 YSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASL 470
            |...:::....|||..|.|..|||..|.|:.|::.....|||.|.::.|:.....||..:|:|.|
  Rat   320 YVASLALAQGSAKKFKYSVDDNQEFLAHGLSNVIPSFLFCIPSAAAMGRTAGLYSTGAKTQVACL 384

  Fly   471 VSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVV 535
            :|...|::.:..|||....||.||||.:|:|.||.|.:|.::|||:....|::...||||::..:
  Rat   385 ISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWISTYIFTI 449

  Fly   536 IIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYM-DLNQ---------HRNAMQVP- 589
            ....::|||.|:..::           :.:||..|.|..:.: |:.:         :.|....|
  Rat   450 CFAANVGLLFGVVCTI-----------AIVLGRFPRAKTLSITDMKEMELKVKTETYDNTENWPP 503

  Fly   590 ----EVRIFRYSGSLNFATS-------------------------LFFRRALYEAVGLDKIPLTK 625
                .|::|  .|||...::                         |.|..|...:..|.||.|.:
  Rat   504 SKSTNVKVF--PGSLKTGSNVRSLSVTPRRMENSQQIKIISINNPLVFLNAKKFSADLMKIILKE 566

  Fly   626 VSSSNS-NSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLS 689
            ...|.: :..||..:::......||...........|..:. |||:.|.|...|..|..||.:|.
  Rat   567 TDGSQALDDVSKCEQNTLLSPLPNGSCTEEASQPCPSEKYS-LVLNCSGLTFFDYTGVSTLVELY 630

  Fly   690 KELKVRGARLLLAS 703
            .:.|.|...:.||:
  Rat   631 LDCKSRSVDVFLAN 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	184/663 (28%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	34/153 (22%)
Slc26a7	XP_038965346.1	sulP	33..673	CDD:273284	184/663 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850