Protein Alignment Prestin and sul1

DIOPT Version :10

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_595773.1
• Gene: sul1 / 2540681
• PomBaseID: SPBC3H7.02
• Length: 877
• Species: Schizosaccharomyces pombe
• Alignment Length: 780
• Identity: 202/780 - (25%)
• Similarity: 318/780 - (40%)
• Gaps: 182/780 - (23%)

  Fly     1 MPSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKY--SIHRDVLTHEVVI---------KQTGYA 54
            :|.| |:|::.|          |.||......|.|  ..:.|.::.:..|         |.|.:.
pombe    17 LPQD-EAPDSVP----------GLVPPPSNFVPVYPEPTYSDTVSKKGTIVRVVRHTASKLTKHG 70

  Fly    55 ARDKSIPSSLRN----------------CWRSWNFFALF--------TGVIPILQWLPQYSPRRD 95
            ...:|: |:|.|                .|...|.|:.|        ..:.||:.|||:|: ...
pombe    71 DSSQSL-STLPNNDISVGEYVEPLPSVPGWLKQNIFSHFGTRLLHYLRSLFPIMNWLPRYN-WNW 133

  Fly    96 LPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMT 160
            |..|.|||.||..:.:|.||:|..:|.:.|..|||.:...|..|....|||.:|||..||.|::|
pombe   134 LVYDFIAGITVGCVVVPQGMSYAKVATLPAQYGLYSSFVGVAIYCIFATSKDVSIGPVAVMSLVT 198

  Fly   161 AKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNAD 225
            :||:   |||.                                                   ..|
pombe   199 SKVI---ANVQ---------------------------------------------------AKD 209

  Fly   226 P-ITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVP 289
            | ....::.|:|||..|.:...:..||||.:...:..|.|.||||.:|.:::..|:..::|....
pombe   210 PNYDAAQIGTTLALLAGAITCGLGLLRLGFIIEFIPVPAVAGFTTGSALNIMAGQVSSLMGYKSR 274

  Fly   290 RHKGA--FKIIYTVIDVIKGVPQTNL-VNFGFCMAVIAFMM--ICNEILKPRLSKKCR-FPLPAE 348
            .|..|  :::|   |..::.:|.|.: ..||.....|.:::  .|..::| |.:|..| |.|...
pombe   275 VHTNAATYRVI---IQTLQNLPHTKVDAAFGLVSLFILYLVRYTCQHLIK-RYTKFQRVFFLTNV 335

  Fly   349 L---IMVIGGTLISKWFNLYVDYNV------NP----VGKIPSGLPE---PVLPR---LDLVPKV 394
            |   :::|.||.||        |.|      ||    :|.:|||..:   ||:.|   .||..::
pombe   336 LRSAVIIIVGTAIS--------YGVCKHRRENPPISILGTVPSGFRDMGVPVISRKLCADLASEL 392

  Fly   395 AVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQD 459
            .|..|.:.:...||..|    |.:.:.|:|.|:|||.|||..|::|..|...|...|.|||.|..
pombe   393 PVSVIVLLLEHISIAKS----FGRVNDYKVIPDQELIAMGATNLIGVFFHAYPATGSFSRSAINA 453

  Fly   460 QTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEM 524
            ::|..:.:..:.:|.:||:.|..:...|..:|..||:.|||.::..:.:..::...|.:...||.
pombe   454 KSGVRTPLGGIFTAGVVVLALYCLTGAFYYIPNAVLSAVIIHSVFDLIIPWRQTLLFWRMQPLEA 518

  Fly   525 FTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEA-------------PGIY 576
            ..:|......|...|:.|:...:|:|...|..:..||....||.:..|             ..||
pombe   519 LIFICAVFVSVFSSIENGIYTAVCLSAALLLFRIAKPSGSFLGILKIANKFDDDENSIDVVRDIY 583

  Fly   577 MDLNQ-----HRNAMQVPE-VRIFRYSGSLNF-----ATSLFFRRALYEAVGLDKIPLTKVSSSN 630
            :.|||     :......|. |.|||...|..:     ..|:...:|           .|.....|
pombe   584 VPLNQKGMNPNLTVRDPPAGVLIFRLQESFTYPNAGHVNSMLTSKA-----------KTVTRRGN 637

  Fly   631 SNSPSKGSKSSYS-PVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKV 694
            :|...|.|...:: |..:....|  .::|:|....:.::||||.:.|||..|.:.|.|..|||::
pombe   638 ANIYKKASDRPWNDPAPRKKKNA--PEVEDTRPLLRAIILDFSAVNHIDTTGVQALVDTRKELEI 700

  Fly   695  694
            pombe   701  700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	PRK11660	82..731	CDD:481320	180/664 (27%)
sul1	NP_595773.1	Sulfate_transp	137..522	CDD:459995	126/454 (28%)
		STAS_SulP_like_sulfate_transporter	597..729	CDD:132913	30/117 (26%)