Protein Alignment Prestin and sulp-7

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_001033571.1
• Gene: sulp-7 / 189195
• WormBaseID: WBGene00012259
• Length: 582
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 199/661 - (30%)
• Similarity: 313/661 - (47%)
• Gaps: 114/661 - (17%)

  Fly    69 RSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAV 133
            :||..:      |||.:|||.||...:|..|||.|.||.|:|:|.||||..|.|:....|||.::
 Worm     7 QSWKNY------IPITKWLPNYSISENLINDIIGGVTVGILNVPQGMAYASLVGLKPVYGLYTSL 65

  Fly   134 FPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLI 198
            ||.|.|||.|||:|:::|.|||.|:|:..     .|:....:|       :.:|||
 Worm    66 FPSLIYMFFGTSRHVALGVFAVVSLMSGS-----CNLRVTQEI-------ISNNGT--------- 109

  Fly   199 NSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPL 263
                   :::||.:...             .|.|..||.|.||::.::|...:...|.|.||:.:
 Worm   110 -------NMTSTEVEAI-------------SINVVKSLGLAVGLIQIIMGLFKANYLISYLSDQI 154

  Fly   264 VNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGV--PQTNLVNFGFCMAVIAFM 326
            :.||||.||.||:||||..:||:::|||.|..|:.:...|:|..:  .:.|::.||..:..|..:
 Worm   155 ILGFTTGAAVHVLTAQLNKILGVALPRHSGIGKLFFIYQDLITAIIGEKVNVITFGASVVAIVIL 219

  Fly   327 MICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLV 391
            .|...||.||...|...|:|.:|.:::.||:|:.||.:...:.|..||.||:|.|.|.||.|.:.
 Worm   220 YISKYILTPRFCAKTLVPIPFDLFLIVIGTIIADWFQVEERWGVKVVGDIPTGFPNPALPDLFMF 284

  Fly   392 PKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSV 456
            ..|..|::|||||:..:.:|||...||||.||:...||.||:||.......|.|.|...:|:|::
 Worm   285 RHVIGDALAIAIVSVVVTVSMGKVIAKKHNYEIDVRQEFFALGIVASTCSMFPCWPATTALARTL 349

  Fly   457 IQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGK 521
            |.|..|..:||:::.||.::.:.|.:||.:...||.|:|:.::||||:.||:..:......:..|
 Worm   350 INDNAGTKTQISAIFSALVLTLVLFFIGQYLEGLPMCLLSCIVIVALRGMFLHLQNFVTLWRVSK 414

  Fly   522 LEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAM 586
            .:...:..||...|.:|:..||.||...:||.          .:|.....:|.:..|........
 Worm   415 YDWAIFAITFFATVCLDVVPGLFIGTIFALLL----------SILRIQRSSPTLLDDDCAESGKT 469

  Fly   587 QVPEVRIFRYSGSLNFATSLFF----------RRALYEAVGLDKIPLTKVSSS-----NSNSPSK 636
            .|    :|       ||:|||:          ::.:.:..|...|....||:.     :|:.|.
 Worm   470 FV----VF-------FASSLFYFNCERFDRKIQKIVAQITGEKDISKAAVSTEDMAMIDSHKPQ- 522

  Fly   637 GSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLL 701
                                        |.::.|.:.:..||::|...|..:.|:|........:
 Worm   523 ----------------------------KTVIFDMNGVSSIDLSGANLLVKIQKDLITNDISFKI 559

  Fly   702 ASPVDRVYDTL 712
            .:|.|.::..|
 Worm   560 RNPSDHIFSFL 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	196/648 (30%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	24/146 (16%)
sulp-7	NP_001033571.1	sulP	14..563	CDD:273284	193/639 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156522
Domainoid	1	1.000	290	1.000	Domainoid score	I830
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69472
Inparanoid	1	1.050	337	1.000	Inparanoid score	I1407
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm14396
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.940