Protein Alignment Prestin and sulp-1

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_491866.2
• Gene: sulp-1 / 183842
• WormBaseID: WBGene00016945
• Length: 729
• Species: Caenorhabditis elegans
• Alignment Length: 742
• Identity: 150/742 - (20%)
• Similarity: 279/742 - (37%)
• Gaps: 170/742 - (22%)

  Fly    35 YSIHRDVLTHEVVIKQTGYAARDKSIPSSLRNCWRSWNFFALFTGVIPILQWLPQYSPRRDLPGD 99
            ::.:|...|:..:.||  :|..|..|.....|.|         |.::.|..|:.:|..:..|..|
 Worm    29 FAKYRKKKTNTELAKQ--FAIGDNWILYQSPNPW---------TQILAITTWINKYHVKDSLGKD 82

  Fly   100 IIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVV 164
            :|....::::.:|..:.:|::.. ...:.:|....|.:.|.|.|:::|.|:|..:..|:|
 Worm    83 LIGALYLSLLLLPQAIGFGVVIN-DVASAVYSMFIPQIIYAFFGSAQHSSLGALSFLSIM----- 141

  Fly   165 DTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITK 229
             .|.:::..|..|
 Worm   142 -IYCSIEYSHSHL---------------------------------------------------- 153

  Fly   230 IEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVL---------- 284
                :|::|....:.|:...|.|..:.|.:|...::||:......:|...|...|
 Worm   154 ----SSISLCCAFIQLMQFLLPLEFIFSYISTSALSGFSVGLFIRIVFRFLPQFLVFRGHDCKST 214

  Fly   285 ---GISVPRH----KGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSK--- 339
               ||.:|..    |...:..|..:..::......:|     ..|:|.|:..  |.|.|||:
 Worm   215 SAVGILLPNTTDNVKRVLQCFYAAVPCLRSADTILIV-----ATVVAAMVFI--IFKWRLSRFLI 272

  Fly   340 -KCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDL-VPKVA------- 395
             |..|..|.|..:::..|||..:|.              ..:......|:|| :||:.
 Worm   273 SKIGFSAPHEFFVLLTVTLIIFFFQ--------------PDVASQASSRIDLSIPKIGLWTLPSF 323

  Fly   396 ---VDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVI 457
               :||.||:|...:..|.:..:.|::..|:|...||||...|.:::...|..:|.:.|...|.|
 Worm   324 NTFLDSFAISIYAMTSHMQITKSIAEEKMYKVHRKQELFCFSIISILSSFFGLLPPSSSYGSSQI 388

  Fly   458 QDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKL 522
            ..::...|.:|:::|....::.:.:..|.|::||.|.:..::|.:....|...|.::
 Worm   389 NIESSKFSLVANVLSLIPTILMVHFGAPLFNALPICAIGIMVITSFNGWFSDLKNIR-------- 445

  Fly   523 EMF---TWISTFLCVVII------DIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMD 578
            |:|   ||.:......|:      ::..|.:..:..|:.|:.:|...|...:|..:.|:.  :.:
 Worm   446 EIFYSSTWDAAIAMAAIVSALIFPNVCTGFICMLFCSIFAVSLKVQFPNVEVLAKLSESH--FAE 508

  Fly   579 LNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALY-EAV---GLDKIPL-TKVSSSNSNSPSK-G 637
            .|::........:||.|.||.|........|..|: :||   ||..|.: |:.:|..|..||. |
 Worm   509 ENRYEGDCLDTPLRIIRLSGPLLSVNCESIRSELFKQAVVVKGLIGIGIGTRTASLRSQCPSAIG 573

  Fly   638 SKSSYSPVSQNGGKAIN-----------------GKLEETSGAFKVLVLDFSMLGHIDVAGCRTL 685
            .|.|... |....:::|                 ...|:|....:.|||..:.:..||......|
 Worm   574 PKFSIQE-SICARESVNLSANITIIQECDVSVALPPSEDTPPIVRFLVLSMNGVTGIDKDMLTCL 637

  Fly   686 TDLSKELKVRGARLLLASPVDRVYDTL 712
            :.:..:|.....::|||.....|.|::
 Worm   638 SQVYGDLSSENIKILLAGVPAFVRDSM 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	140/695 (20%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	37/154 (24%)
sulp-1	NP_491866.2	sulP	66..685	CDD:273284	140/694 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3169
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.830