Protein Alignment Prestin and sulp-3

DIOPT Version :10

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_509424.2
• Gene: sulp-3 / 181094
• WormBaseID: WBGene00018283
• Length: 782
• Species: Caenorhabditis elegans
• Alignment Length: 688
• Identity: 185/688 - (26%)
• Similarity: 329/688 - (47%)
• Gaps: 64/688 - (9%)

  Fly    81 IPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTS 145
            :||:.|||:|.......||:..|.|:|:.::|.|:|...:.||....|||.|:||...|:|.|||
 Worm    45 LPIITWLPKYDWSHSFFGDLSGGLTMAVFSVPQGIALASITGVPPVYGLYTAIFPSFLYIFFGTS 109

  Fly   146 KHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTA----TASPLL-LINSSALAD 205
            ||.::|.|||.|:||...::         :::...|  ...|.||    |...|| ..|.:||
 Worm   110 KHNALGGFAVLSLMTHGAIE---------KVMLRTA--TSYNATAYVNHTLDELLDKENETAL-- 161

  Fly   206 SVSSTTISPFQLLNS-------------TLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSS 257
             :|:||:  .|:|.:             |....|:.:|.|||::....|::.:.|...||..|:|
 Worm   162 -ISNTTL--MQILGNETSFVEEVTMEMWTEGVTPVKQIHVATTIIFLAGVIQVFMGVFRLQYLTS 223

  Fly   258 LLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAV 322
            |.||.:::||......||..||:.::|||.:||..|...:.|.:.|:::.:...::......::.
 Worm   224 LFSEQVMSGFVVGGGIHVFFAQIGNMLGIELPRRSGPGYLYYRIWDLVENLDNVHIPTVCISLSS 288

  Fly   323 IAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPR 387
            ..|::...|.|.|.|:....:|:|.||::|:.|...:.:..|.:.::|..||.||:..|.|.|||
 Worm   289 FLFLVFGKEYLAPWLNSAFNYPVPFELVLVVVGITATNYAELSLRHDVKVVGNIPTEFPPPSLPR 353

  Fly   388 LDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSL 452
            .||:..:.:::.||||...:|.:::.....|::.|::...|||:|:|...::...|...|:....
 Worm   354 FDLIRHIGLNAAAIAITAVAIHITVAKVVEKRYKYKINHGQELYALGFVGVLSSFFPVFPVTSGF 418

  Fly   453 SRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFS 517
            :|||:....||.:|:..|.|:..::..::.|||....||:|:|:.:||.|.|.|..:..|||...
 Worm   419 ARSVVGAAVGGSTQLTCLFSSLALLSVILCIGPALEYLPQCILSAMIIFAQKGMLEKFGELKSLW 483

  Fly   518 KQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQH 582
            ...|::...|:.:|...|..|:..|||:.|..::|...|:..:|....|....:... |.:..:.
 Worm   484 PVFKIDFTIWLMSFFLTVCYDMGEGLLMAIGFAVLTTIIRTQRPKWHFLSRDDDTEN-YKETKKR 547

  Fly   583 RNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAV-------GLDKIPLTKVSSSNS----NSPSK 636
            ........|.|||....|.|.:|..|..::::.|       ....:.:.:::|..|    :|..|
 Worm   548 DLERIQGNVCIFRMDAPLIFTSSDRFTMSVWQCVKKWERCKSESFVTIEQMNSDRSADIFDSKLK 612

  Fly   637 GSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGAR--- 698
            .::..:             |.::.|.....||:|.....::|..|..||..:..:|:..|.:
 Worm   613 SARRRW-------------KRDQKSENRCKLVIDCDGFPYVDYLGLSTLKSVYVDLQAAGIQCFF 664

  Fly   699 LLLASPVDRVYDTLVHSMALSEGPFEIFPTLHDCVEYA 736
            ::..|.:.:::........:.|.  ::|..:.|.|:.|
 Worm   665 VVQKSDLKKLFRATDFYEVVDES--KVFNKVGDAVKAA 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	PRK11660	82..731	CDD:481320	182/680 (27%)
sulp-3	NP_509424.2	Sulfate_transp	60..496	CDD:459995	137/451 (30%)
		STAS	551..696	CDD:426404	27/159 (17%)