Protein Alignment Prestin and LOC1280392

DIOPT Version :10

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_061515962.1
• Gene: LOC1280392 / 1280392
• VectorBaseID: AGAMI1_013838
• Length: 680
• Species: Anopheles gambiae
• Alignment Length: 641
• Identity: 156/641 - (24%)
• Similarity: 273/641 - (42%)
• Gaps: 146/641 - (22%)

  Fly    17 NTNGNGGSVPSKPKIQPKYSIHRDVL----THEVVIKQTGYAARD--KSI-PSSLRNCWRSWNFF 74
            |.:|..||..|. .:.|   ||:||:    ::|.::.....:..|  |:| |.:.|.|.......
Mosquito    46 NIHGLSGSQHSL-SVPP---IHKDVVGYRGSNEFILTDDKQSTMDQIKAIGPWARRKCKNMCRRK 106

  Fly    75 ALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAY 139
            .|:..| |:|.|||:|: ..|..||::||.||.:..||..:||..:||:.|..|||.:......|
Mosquito   107 ILYKRV-PVLNWLPKYN-MDDAVGDLVAGITVGLTVIPQALAYSSIAGLPAAYGLYGSFIGCFVY 169

  Fly   140 MFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALA 204
            :.||:.|.:.:|..|:||::|.:..|                 |:...
Mosquito   170 ILLGSCKDVPMGPTAIASLLTFQACD-----------------GVWQR----------------- 200

  Fly   205 DSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTT 269
                                        |..|....|::.|||....||.|...:|.|:.:|||:
Mosquito   201 ----------------------------AVLLCFLTGLIELLMGLFGLGFLIDFVSGPVSSGFTS 237

  Fly   270 AAACHVVTAQLKDVLGISVPRHKGAFKIIY--TVIDVIKGVPQTNLVNFGF-CMAVIAFMMI--- 328
            |.:..::::|:||:|||:.   ||...|..  ::||.|... |......|| |:.|:..|.:
Mosquito   238 AVSLIILSSQVKDLLGIAA---KGNTFIEQWSSIIDDIHNT-QVGDALMGFICIVVLLLMRLLPR 298

  Fly   329 --------CNEILKPRLSKKCRFPL----PAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLP 381
                    |::.:..::..|..:.:    .|.:::|.||...:.:.|....:.:  :|.:|||||
Mosquito   299 IKVGPPDACDQSVAQKIINKSLWLIGTARNAIIVVVCGGIGAAFYENGKEPFRM--IGDVPSGLP 361

  Fly   382 EPVLPRLDLVPKV-------------------AVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPN 427
            ....|... ||:|                   .:.|:.|.|...:::.::.:..|...|..|...
Mosquito   362 SVQAPPFS-VPEVRDANGTIVQEYESFGDLLQGLGSMLIVIPLIALLENIAICKAFADGKPVDAT 425

  Fly   428 QELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPR 492
            |||.|:|:.|:........|...:|||..:.:.:|..:....|.:..||::.|::..|:|..:||
Mosquito   426 QELIAIGVSNIANSFVQGYPGTGALSRGAVNNASGVRTPFGGLYTGLLVILALLFFTPYFFYIPR 490

  Fly   493 CVLAGVIIVALKPMFM-QAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLAL-- 554
            ..||.:||.|:  :|| :.:.:|...:..|.::...|:||:..:.:.::.|:|:||.:::|.:
Mosquito   491 AALAAIIIAAV--IFMIEVRVVKPMWRSKKTDLIPGIATFIACLALPLEYGILVGIGLNILFILY 553

  Fly   555 -------------------YIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEV 591
                               |:. |.|..||:  .|....:...:|:|....|:|.|
Mosquito   554 HAARPKIHMDQAVTPCGVKYLM-LTPDRCLI--FPSVDYVRNLINKHGLKSQIPVV 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	PRK11660	82..731	CDD:481320	137/569 (24%)
LOC1280392	XP_061515962.1	None