Protein Alignment Prestin and slc26a7

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_002934468.3
• Gene: slc26a7 / 100493278
• XenbaseID: XB-GENE-985132
• Length: 668
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 183/653 - (28%)
• Similarity: 318/653 - (48%)
• Gaps: 88/653 - (13%)

  Fly    81 IPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTS 145
            :|||:|.|:||.|..|..|.::|..:::..:..|:|:.:::.|....|||.:.||.|.|...|..
 Frog    46 LPILEWAPKYSVRESLLPDTVSGLMLSVQQVTQGLAFAVMSSVHPVFGLYGSFFPPLIYAVFGMG 110

  Fly   146 KHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSST 210
            :|:..||||:.|:::|..|:         :::|                       ..:.:||::
 Frog   111 RHLVTGTFAITSLISASAVE---------RLVP-----------------------PYSGNVSNS 143

  Fly   211 TISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHV 275
            ::.|..|....:.     :|.||.::....||:.:.:....||..:.|||||:|:..||.||.||
 Frog   144 SLGPLGLSEFEMQ-----RIGVAAAVTFLGGIIQICLFVCNLGCATFLLSEPVVSSMTTGAATHV 203

  Fly   276 VTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTN---LVNFGFCMAVIAFMMICNEILKPRL 337
            ||:|:|.:||:.:|...|...:....|.::|.:....   ::....|:.|:..:...|:..|.|:
 Frog   204 VTSQVKYLLGMKMPYISGPLGMFNIYIYILKNITTATVAAVITSVICLVVLVLVKELNQRYKSRI 268

  Fly   338 SKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIA 402
                :..:|.:||::|..:|:..:.|:..:|||..||.:|.|:|.|..|.:.::..:.|:..::|
 Frog   269 ----KMEIPIDLILIILTSLVCYFINMEHNYNVEVVGLLPKGIPIPQAPPMGILSDIVVEGFSVA 329

  Fly   403 IVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQI 467
            :|.|::.:.:....|||..|.|..||||.|.|:.|::.....|||.|.:.:||.:....|..||:
 Frog   330 LVGYTVSIFLAYNSAKKFKYSVDENQELLANGLTNVIPSFLFCIPNAGAPARSFVLFSNGAKSQV 394

  Fly   468 ASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFL 532
            |||:|..:|::.:.:||||...||.|.||.:|:||||.|.:|..:|||:....|::...||.|::
 Frog   395 ASLISCVIVLLVIYFIGPFLCWLPMCALASIIVVALKGMLIQFNDLKKYWNVDKVDWVIWICTYV 459

  Fly   533 CVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYS 597
            ..:....:||||.|:..|:....::           :..|..:::   .|.:|         .|:
 Frog   460 FTICFAANIGLLFGVLFSIALGMLR-----------LSRAKTLHL---VHWDA---------EYN 501

  Fly   598 GSLNFATSLFFRRALYEAVGLD---------KIPLTKVSSSNSNSPSKGSKSS--YSPVSQNGGK 651
            ..|....|.||:.....:||:.         :..|.|::...:.:..:..|:.  .|||| ||..
 Frog   502 KMLEGLNSGFFQTVKIVSVGMPLFFLNAKKFQADLLKMNDKLTGNFVRKQKTDLLLSPVS-NGDS 565

  Fly   652 AINGK---LEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLV 713
              ||:   |:........|:||.|.:...|..|...||.:..|||.:|..:||..    ..|:||
 Frog   566 --NGEAPILQPQRSQSYTLILDCSGITCYDYTGVTILTQICLELKGQGTTVLLTG----CNDSLV 624

  Fly   714 HSM 716
            .::
 Frog   625 KAL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	183/652 (28%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	38/149 (26%)
slc26a7	XP_002934468.3	sulP	47..646	CDD:273284	183/652 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020