Protein Alignment Prestin and slc26a4.2

DIOPT Version :10

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_031754875.1
• Gene: slc26a4.2 / 100485000
• XenbaseID: XB-GENE-22062181
• Length: 389
• Species: Xenopus tropicalis
• Alignment Length: 348
• Identity: 83/348 - (23%)
• Similarity: 150/348 - (43%)
• Gaps: 59/348 - (16%)

  Fly   438 MVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVA 502
            |.||.|||...:.:|||:.||:..||.:||||.|||.::::.::.:|.....|.:.||:.::||.
 Frog     1 MFGGAFSCFCASTALSRTAIQESIGGKTQIASAVSAGILLIAILALGKLLEPLQKSVLSAIVIVN 65

  Fly   503 LKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLG 567
            ||.||...|::.:..|:.:.:..:|:.:.:..:|:.:|||||:|:...||.:.|:...|....||
 Frog    66 LKGMFWLIKDVPRLWKESRWDSVSWVVSCIAAIILGLDIGLLVGLLFGLLTVMIRVQFPSCSSLG 130

  Fly   568 YMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKI--------PLT 624
            .: :...||.::..:::..:...::|.|:|.::.:......:..:...||.|.:        .|.
 Frog   131 NV-QGTDIYKNVKIYKHISEPAGMKIVRFSSAIFYGNVEGLKNGIKSIVGFDAVRVFNKRNKALR 194

  Fly   625 KVS--------SSNSN--------------------------SPSKGSKSSYSPVSQNGGKAING 655
            |:.        ||..|                          ||...:|.....|..|....:..
 Frog   195 KIKKLIKKGEISSLQNGTINNTGTDNEAFERDDDPEDQEKVDSPEVQTKEVEIQVDWNSELPVKV 259

  Fly   656 KLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSE 720
            .:.:.|  ...::.||..:..:|....::|..:..|.:.......:|:..|.|.      ..:..
 Frog   260 SVPKVS--IHSIIFDFGQILFLDSVAMKSLKSIINEFRRIDVLPYIAACDDNVL------AQMER 316

  Fly   721 GPF-------EI-FPTLHDCVEY 735
            |.|       || |.|:||.|.|
 Frog   317 GNFFDDTIKPEICFMTVHDAVLY 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	PRK11660	82..731	CDD:481320	79/342 (23%)
slc26a4.2	XP_031754875.1	PRK11660	<3..336	CDD:481320	79/341 (23%)