Protein Alignment Prestin and slc26a10

DIOPT Version :9

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_001921766.4
• Gene: slc26a10 / 100150270
• ZFINID: ZDB-GENE-030131-9845
• Length: 690
• Species: Danio rerio
• Alignment Length: 670
• Identity: 231/670 - (34%)
• Similarity: 366/670 - (54%)
• Gaps: 67/670 - (10%)

  Fly    81 IPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTS 145
            :|:..|||:|..|:.|.||||||.||.|::||.|||:.:|..|:...|||.:.|||:.||..||.
Zfish    56 LPVCSWLPKYKLRKWLLGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTG 120

  Fly   146 KHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSST 210
            .|:|.|||||.|:||..||:         |::||              ||.|.:||..|....:
Zfish   121 HHVSTGTFAVLSLMTGSVVE---------QLVPI--------------PLALNSSSPEAAEFEA- 161

  Fly   211 TISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHV 275
                             .:|.||:::|...||:.|.|..|:||.||:.||||:|..||:|||.||
Zfish   162 -----------------QRIGVASAVAFLSGIMMLCMCGLQLGFLSTYLSEPIVKAFTSAAAFHV 209

  Fly   276 VTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKP----- 335
            ..:||:.:||:.:||:.|||.:..|:..|::.||.|||       |.:...::|..:|.|
Zfish   210 TVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNL-------AELVISLLCLAVLVPVKEVN 267

  Fly   336 -RLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSI 399
             |..::.|.|:|.|:|.||..|.|:..|:|...|::..||.||:|.|||.||.|:.||::|.|::
Zfish   268 SRFRERLRTPIPVEIITVIIATGITYAFSLDSKYDIQIVGHIPAGFPEPRLPALETVPEIAGDTV 332

  Fly   400 AIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGV 464
            ||.:|.|::.:|:.:.:|.||||.:.|||||.|.||.|.|...|:|.|.:.:|:.:.|.:..||.
Zfish   333 AITLVAYAVSVSLAMIYADKHGYSIDPNQELLAHGISNTVSSLFTCFPNSATLATTNILESAGGH 397

  Fly   465 SQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWIS 529
            :|:|.|.::.:|::.|:.|||.|..||:.|||.:.:.:|:.||:|.::|.:..:..|::...|:.
Zfish   398 TQLAGLFTSLVVLIVLLLIGPLFYFLPKAVLACINVTSLRQMFLQFQDLPELWRISKIDFMVWLV 462

  Fly   530 TFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIF 594
            |:|.||::::|:||.||:..|::.:..:..:....:||...... ||..:|.|....:||.|:|.
Zfish   463 TWLSVVVLNVDLGLAIGMVFSMMTVVCRTQRASCSVLGRAANTE-IYRSINNHNKCYEVPGVKIL 526

  Fly   595 RYSGSLNFATSLFFRRALYEAVGLDKIPLTKVSSSNS--NSPSKGSKSSYSPVSQN-GGKAINGK 656
            .|:|.:.:....||:..:.:.:||..   .::.|...  .:..|..:.:.|.|.|. ...:.:.|
Zfish   527 TYNGPIYYGNRSFFKADMAQLLGLTP---ERIRSREKALKAIEKREREAISTVEQGVADSSFSSK 588

  Fly   657 -----LEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSM 716
                 .|...|..:.:::|.|.:..:|:||.|....:..|.:..|.|:.||:..:.|...|..|.
Zfish   589 NDLFTSEMAEGEVQAVLIDCSSVIFVDIAGARLFIQMCMECQKIGVRIYLANCNESVLKILTSSG 653

  Fly   717 ALS-EGPFEIFPTLHDCVEY 735
            .:: ..|..||.|:||.|.|
Zfish   654 LMNYMNPQHIFVTIHDAVVY 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	sulP	82..731	CDD:273284	227/663 (34%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	37/156 (24%)
slc26a10	XP_001921766.4	Sulfate_transp	57..670	CDD:332851	228/664 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574457
Domainoid	1	1.000	299	1.000	Domainoid score	I1407
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	386	1.000	Inparanoid score	I1977
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm25589
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.890