Protein Alignment Prestin and slc26a9

DIOPT Version :10

• Sequence 1: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_031751455.1
• Gene: slc26a9 / 100124761
• XenbaseID: XB-GENE-996559
• Length: 839
• Species: Xenopus tropicalis
• Alignment Length: 796
• Identity: 224/796 - (28%)
• Similarity: 364/796 - (45%)
• Gaps: 136/796 - (17%)

  Fly    30 KIQPKYSIHRDVLTHEVVIKQTGYAARDKSIP-----SSLRNCWRS--WNF-FALFTGVIPILQW 86
            |::|:|.|.|...:.|:..::  |..:.:|.|     ..|.:|..|  .|| |.||    |||.|
 Frog    46 KVRPRYIIDRPAYSVELFNEE--YEKKIRSYPIGGKARKLFSCSTSKIKNFIFRLF----PILSW 104

  Fly    87 LPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIG 151
            ||:|:.:.:|..|.:.|.:...:.||.|||:.:||.:...||||.:.||::.|.|:|....:..|
 Frog   105 LPKYNIKGNLLNDALGGISAGTIQIPQGMAFALLANLPPVNGLYSSFFPLVVYFFMGGIPQMVPG 169

  Fly   152 TFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQ 216
            ||||.|::...|.         .::.|.:.| :..|||                  |:.|....:
 Frog   170 TFAVISIIVGNVC---------LKLAPESEF-VTINGT------------------SNVTFIDIE 206

  Fly   217 LLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLK 281
            .:|.       .::.::.:||....|:.:.::|::.|.::..|||..:.||.|||...::.:.||
 Frog   207 AMNG-------KRMHISATLACLTAIIQIALSFVQFGFVAIYLSESFIRGFMTAAGLQILISVLK 264

  Fly   282 DVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLP 346
            .:.|:|:|.:.|...||||.||:.|.:|:||:.:..|.:.....::|..| |..:...|.|||:|
 Frog   265 YIFGVSIPPYSGVLAIIYTFIDICKELPKTNVASLIFALISTVLLIIVKE-LNMKFMHKIRFPIP 328

  Fly   347 AELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVTYSIIMS 411
            .|:|:||..|.:|..|.|...|::|.||.||.|.|.|.:|.:....::...:.::|||.|.|.::
 Frog   329 MEIIIVIVATAVSGSFKLPERYHMNVVGHIPLGFPSPTVPNVTQWDEMVGTAFSLAIVGYVINLA 393

  Fly   412 MGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLV 476
            ||.|...|||::|..|||:.|:|.||..|..|....:.|:||.::..|..||.|||||......|
 Frog   394 MGRTLGAKHGFDVDANQEMLALGSGNFFGSFFFIHVICCALSVTLAVDGAGGKSQIASFFVMMSV 458

  Fly   477 VVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDI 541
            :||::.:|.:.:.||:.||..:|.|.||....|..:.....|:.||:...|:.:|....|:.:..
 Frog   459 MVTILALGTYLNPLPKSVLGALIAVNLKNSLKQLSDPFYLWKKSKLDCLVWLVSFFSTFILGLPY 523

  Fly   542 GLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSL 606
            ||.:|:..|:|.:...........|..: .|..||::...:.....:..::|..|...|.||.|.
 Frog   524 GLAVGVAFSILVVIFNTQFRNGSSLNQV-TATDIYVNPKVYSKVQPIDGIKIVTYCSPLYFANSE 587

  Fly   607 FFRRALYEAVGLD--KIPLTK-------------------------------------------V 626
            .||:.:.:..|||  |:.|:|                                           .
 Frog   588 IFRQKVIKKTGLDPGKVYLSKKKYLKQQEQELKKKEQKKKRGSLFMKNKTLSLQELQEDFDGVSP 652

  Fly   627 SSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGA---------------------------- 663
            :.||:||...|:.|:.|.:|.|         ..|||:
 Frog   653 TDSNNNSTVNGTASAISYISSN---------TLTSGSQTTENVQNGFSTPAQTQDPIIAAPPIVN 708

  Fly   664 FKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSEGPFE---I 725
            |..:::|.|.:..:|:.|.:.|..|....:..|..:.||....:|||.:.:....:||..:   :
 Frog   709 FHTVIIDMSGVCFVDLMGIKALGKLCTSFQRIGVNVYLADVQAQVYDDIENGGMFAEGSLDRKHL 773

  Fly   726 FPTLHDCVEYANACRT 741
            |.|:||.|.||.|..|
 Frog   774 FITVHDAVLYAEANNT 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prestin	NP_649024.1	PRK11660	82..731	CDD:481320	200/724 (28%)
slc26a9	XP_031751455.1	PRK11660	100..604	CDD:481320	168/540 (31%)
		STAS_SulP_like_sulfate_transporter	<708..777	CDD:132913	16/68 (24%)