Protein Alignment Tsp74F and CD151

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_004348.2
• Gene: CD151 / 977
• HGNCID: 1630
• Length: 253
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 75/255 - (29%)
• Similarity: 125/255 - (49%)
• Gaps: 25/255 - (9%)

  Fly     1 MG-FSSRMDCCGQF-VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLL 63
            || |:.:...||.. :||.||..|...::.|..|..:.:|||..:|....||.:..:....|:|:
Human     1 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILV 65

  Fly    64 VTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTM 128
            |...::.:...|||....||.:.||..|||::.::|:..:|.|:|.|.:.:::...:::.::.||
Human    66 VAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

  Fly   129 AL---YGSRREITQAWDLTQERLQCCGVDTWHDW--------NRYG--PVPESCCQELFG--GQR 178
            ..   ......:|.|.|..|:...|||.:...||        ...|  .||:|||:.:..  |||
Human   131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQR 195

  Fly   179 KECTIFPTITNLY--NQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMIE 236
            ...      :|:|  ..||:.....||::|..|||...|.:|.:.:|||||:|.|:..::
Human   196 DHA------SNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	70/235 (30%)
		NET-5_like_LEL	110..207	CDD:239418	27/113 (24%)
CD151	NP_004348.2	Tetraspanin	16..246	CDD:459767	70/235 (30%)
		CD151_like_LEL	112..220	CDD:239408	27/113 (24%)