Protein Alignment Tsp74F and CD81

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 61/221 - (27%)
• Similarity: 101/221 - (45%)
• Gaps: 33/221 - (14%)

  Fly    27 VGGAIVFCLTLWTLVDRSFVNEL---LG----TNLFSGAVYVLLVTSIIICLVSFLGCVGAGKEV 84
            :.|.::..:.||...|....|.|   ||    .|.|...:|:|:....::..|.||||.||.:|.
Human   122 LAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQES 186

  Fly    85 KCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQ--EMRSTMALYGSRREITQAWDLT-QE 146
            :|||.|:|..:.::|...:..|:.|:|.::::.:.::|  :.....|:........:|...| .|
Human   187 QCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHE 251

  Fly   147 RLQCCGVDTWHDW------NRYGPVPESCCQELFGGQRKECTIFPTITNLYNQGCLYVTTNFIRD 205
            .|.|||..|....      |...|...:....||   :::|  ...|.:|:: |.||
Human   252 TLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLF---KEDC--HQKIDDLFS-GKLY-------- 302

  Fly   206 HAAVIGGTSIAVAILMIFGMIFSCLL 231
               :||..:|.||::|||.||.|.:|
Human   303 ---LIGIAAIVVAVIMIFEMILSMVL 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	61/221 (28%)
		NET-5_like_LEL	110..207	CDD:239418	21/105 (20%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	61/221 (28%)