Protein Alignment Tsp74F and CD63

DIOPT Version :9

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001244318.1
• Gene: CD63 / 967
• HGNCID: 1692
• Length: 238
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 61/238 - (25%)
• Similarity: 105/238 - (44%)
• Gaps: 27/238 - (11%)

  Fly    10 CGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNEL-LGTNLFSGAV------YVLLVTSI 67
            |.:|:.|.|.:|           ||.....|:......:| |...:..||.      .|::...:
Human     9 CVKFLLYVLLLA-----------FCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGV 62

  Fly    68 IICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYG 132
            .:.||:|:||.||.||..||::|:.|.::|:.:..:...:.|||||::|........|..|..|.
Human    63 FLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYP 127

  Fly   133 SRREITQAWDLTQERLQCCGVDTWHDWNRY-----GPVPESCCQELFGGQRKECTIFPTITNLYN 192
            .........|..|...:|||...:.||.:.     ..||:|||..:..|    |.|......::.
Human   128 KNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVG----CGINFNEKAIHK 188

  Fly   193 QGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
            :||:.....::|.:..|:...::.:|.:.:.|::|:|.|...|
Human   189 EGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSI 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	57/228 (25%)
CD63	NP_001244318.1	Tetraspannin	10..227	CDD:395265	58/231 (25%)
		CD63_LEL	105..203	CDD:239419	26/101 (26%)
		Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731	234..238

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4418
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840