Protein Alignment Tsp74F and CD53

DIOPT Version :9

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 69/234 - (29%)
• Similarity: 120/234 - (51%)
• Gaps: 31/234 - (13%)

  Fly     1 MGFSSRMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFS---GAVYVL 62
            ||.||.     :.:||.||..|.:.::.|..:....::.|:..:|  .:|..||.|   |.|:|
Human     1 MGMSSL-----KLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNF--GVLFHNLPSLTLGNVFV- 57

  Fly    63 LVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRST 127
             :...||.:|:||||:|:.||.||||:::||::.::.:..:...:|.:|:.:::.:.:.:.:..:
Human    58 -IVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDS 121

  Fly   128 MALYGSRREITQAWDLTQERLQCCGVDTWHDWNRYGPVPESCCQELFGGQRKECTIFPTITNLYN 192
            :..|.|......|||..|..|||||::...||.. || |.||..:     ||       :...|.
Human   122 IHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTS-GP-PASCPSD-----RK-------VEGCYA 172

  Fly   193 QGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLL 231
            :..|:..:||:     .||..:|.|.::.:.||.|:..|
Human   173 KARLWFHSNFL-----YIGIITICVCVIEVLGMSFALTL 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	64/219 (29%)
CD53	NP_000551.1	Tetraspannin	9..206	CDD:366035	64/219 (29%)
		CD53_like_LEL	104..186	CDD:239417	25/100 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910