Protein Alignment Tsp74F and CD37

DIOPT Version :9

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 76/276 - (27%)
• Similarity: 126/276 - (45%)
• Gaps: 60/276 - (21%)

  Fly     5 SRMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDR-SFVNELLGTNLFSGAVY-------- 60
            |..:.|...:||.||:.|...||.|:::||..:|.|:|: |||:       |.|..:
Human     2 SAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVS-------FVGLAFVPLQIWSK 59

  Fly    61 VLLVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMR 125
            ||.::.|....::.||||||.||::|||..||.::.|:|.|.:..|:|....|.::::::|..:.
Human    60 VLAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVE 124

  Fly   126 STMALYGSRREIT---QAWDLTQERLQCCGVDTWH---DW----------NRYGPVPESCCQ--- 171
            .|:..||:..|.|   ::||..|.:|:|||   ||   ||          :....||.||..
Human   125 KTIQKYGTNPEETAAEESWDYVQFQLRCCG---WHYPQDWFQVLILRGNGSEAHRVPCSCYNLSA 186

  Fly   172 ---------------ELFGGQRKE------CTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSI 215
                           ...|...:.      |.: |..:::|.:||......::.::...|.|..:
Human   187 TNDSTILDKVILPQLSRLGHLARSRHSADICAV-PAESHIYREGCAQGLQKWLHNNLISIVGICL 250

  Fly   216 AVAILMIFGMIFSCLL 231
            .|.:|.:..|:.|..|
Human   251 GVGLLEMTVMVLSVQL 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	73/265 (28%)
CD37	XP_005259492.1	Tetraspannin	26..269	CDD:278750	67/252 (27%)
		CD37_CD82_like_LEL	108..243	CDD:239413	28/138 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910