Protein Alignment Tsp74F and TSPAN18

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 76/254 - (29%)
• Similarity: 122/254 - (48%)
• Gaps: 37/254 - (14%)

  Fly    10 CGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTN--LFSGAVYVLLVTSIIICLV 72
            |...:||.:|:.||.||:|||.:..:.:|.:||.:...|::..|  |.:|| |:||....::.|:
Human    15 CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGA-YILLAMGGLLFLL 78

  Fly    73 SFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERV-QQTMRQEMRSTMALYGSRRE 136
            .||||.||.:|.|||||.:|:.:.::|:..|...:|.::|||.: ::...:|:............
Human    79 GFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNNDTDV 143

  Fly   137 ITQAWDLTQERLQCCGVDTWHDWNRYGP------------------VPESCC----QELFGG--Q 177
            .:..|:.......||||:        ||                  |||:||    |...|.  .
Human   144 FSATWNSVMITFGCCGVN--------GPEDFKFASVFRLLTLDSEEVPEACCRREPQSRDGVLLS 200

  Fly   178 RKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMIE 236
            |:||.:..::. |..|||..|..|....:..:.|..:|.|..:.:|.|||:..||..|:
Human   201 REECLLGRSLF-LNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	73/245 (30%)
		NET-5_like_LEL	110..207	CDD:239418	27/121 (22%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	73/244 (30%)
		uroplakin_I_like_LEL	115..228	CDD:239409	27/121 (22%)