Protein Alignment Tsp74F and UPK1B

DIOPT Version :9

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 53/265 - (20%)
• Similarity: 93/265 - (35%)
• Gaps: 81/265 - (30%)

  Fly     9 CCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVS 73
            |||     ....|..:.||...    .:|:.|::.:..:::.      ||.::.:...|.:..:|
Human    24 CCG-----IALTAECIFFVSDQ----HSLYPLLEATDNDDIY------GAAWIGIFVGICLFCLS 73

  Fly    74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQ---TMRQEMRSTMALYGS-- 133
            .||.||..|..:.:||.|||::.:|:...:...:..     ..||   |....::..:..|.:
Human    74 VLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITA-----ATQQDFFTPNLFLKQMLERYQNNS 133

  Fly   134 ---------RREITQAWDLTQERLQCCGVDTWHDWNRYG------------PVPESCCQELFGGQ 177
                     ...:|:.||....:..||||:...||.:|.            |.|..||
Human   134 PPNNDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQCC------- 191

  Fly   178 RKECTIFPTITNL-----------------YNQGCLYVTTNFIRDHA---AVIGGTSIAVAILMI 222
                    .:.||                 :||||..:.:..:..||   |..|...:.....::
Human   192 --------VMNNLKEPLNLEACKLGVPGFYHNQGCYELISGPMNRHAWGVAWFGFAILCWTFWVL 248

  Fly   223 FGMIF 227
            .|.:|
Human   249 LGTMF 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	50/260 (19%)
UPK1B	NP_008883.2	Tetraspannin	10..258	CDD:278750	53/265 (20%)
		uroplakin_I_like_LEL	118..230	CDD:239409	21/126 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910