Protein Alignment Tsp74F and TSPAN7

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 63/236 - (26%)
• Similarity: 107/236 - (45%)
• Gaps: 23/236 - (9%)

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGCV 78
            :|..|.|.:||.::.|.|:..:.:|..:.......|:..| .:.|.|||:.|...|.:....||.
Human    15 LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAEN-STNAPYVLIGTGTTIVVFGLFGCF 78

  Fly    79 GAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSRREITQAWDL 143
            ...:....:|..|.:.::|||:..|:.|:.|:|||..::.|..:.....|..|....|.::|.|.
Human    79 ATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGNDERSRAVDH 143

  Fly   144 TQERLQCCGVDTWHDWN------RYGPVPESCCQELFGGQRKEC--------TIFPTITNLYNQG 194
            .|..|.||||..:.:|:      .:| :|.|||.     ...:|        |:..|..|  .:|
Human   144 VQRSLSCCGVQNYTNWSTSPYFLEHG-IPPSCCM-----NETDCNPQDLHNLTVAATKVN--QKG 200

  Fly   195 CLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
            |..:.|:|:..:..:|.|.:..:|...:.||:.:|.|...|
Human   201 CYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	62/232 (27%)
		NET-5_like_LEL	110..207	CDD:239418	29/110 (26%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	62/232 (27%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	29/110 (26%)