Protein Alignment Tsp74F and Tspan2

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_081809.2
• Gene: Tspan2 / 70747
• MGIID: 1917997
• Length: 221
• Species: Mus musculus
• Alignment Length: 253
• Identity: 64/253 - (25%)
• Similarity: 103/253 - (40%)
• Gaps: 65/253 - (25%)

  Fly     1 MG-FSSRMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLW-----TLVDRSFVNELLGTNLFSGAV 59
            || |...:.|    :||.|...|.:.::.|:.|....||     |:.|.|  :|......|...:
Mouse     1 MGRFRGGLRC----IKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLS--SEDKSPEYFYVGL 59

  Fly    60 YVLLVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRE---RVQQTMR 121
            |||:....::..|.|.||.||.:|.:|:|.::|..:.::|...:..||..::.::   |..|:|.
Mouse    60 YVLVGAGALMMTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMY 124

  Fly   122 QEMRSTMALYGSRREITQAWDLTQER-------------LQCCGVDTWHDWNRYGPVPESCCQEL 173
            :|..|               |..::|             .||||.::...      |..:|.:||
Mouse   125 EEAYS---------------DYLKDRARGNGTLITFHSAFQCCGKESSEQ------VQPTCPKEL 168

  Fly   174 FGGQRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLL 231
            .|                ::.|:......|.....:||...|.:|.|.|||||||.:|
Mouse   169 PG----------------HKNCIDKIETVISAKLQLIGIVGIGIAGLTIFGMIFSMVL 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	60/239 (25%)
		NET-5_like_LEL	110..207	CDD:239418	18/112 (16%)
Tspan2	NP_081809.2	Tetraspanin	11..212	CDD:459767	60/239 (25%)