Protein Alignment Tsp74F and cd37

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001015801.2
• Gene: cd37 / 548518
• XenbaseID: XB-GENE-5831804
• Length: 270
• Species: Xenopus tropicalis
• Alignment Length: 254
• Identity: 74/254 - (29%)
• Similarity: 119/254 - (46%)
• Gaps: 29/254 - (11%)

  Fly    10 CGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAV--YVLLVTSIIICLV 72
            |....||.||:.|.:.|:.|.::.|..||.|.||.....::|:::.:..|  ||.....|:..|:
 Frog     6 CLSVTKYFLFVFNLLFFILGGVLLCFGLWILFDRGSFATMIGSSVPTLKVWSYVFSGVGILTMLL 70

  Fly    73 SFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQ---TMRQEMRSTMALYGSR 134
            .||||:|:.||:||||..||..:.|:|...:..|||.|..|..:..   |:.:.:.....||.::
 Frog    71 GFLGCLGSLKEIKCLLGFYFAFLLLLFSAQITIGVLVYTQRNSLSTRLGTIVESVIKDYGLYANQ 135

  Fly   135 REITQAWDLTQERLQCCGVDTWHDWNRYGPVPES------C-CQEL----FGGQRKECTIFPTIT 188
            .::.:.||..||::||||..|..||.:...:..:      | |:.:    ........|.||...
 Frog   136 TDLEEGWDFAQEKMQCCGWYTPDDWMKNQKIQNTSVSLYPCSCRNVSAFHTNSSANSSTEFPEAK 200

  Fly   189 ------------NLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFS-CLLFNM 234
                        .:|..||:.....|:.:::..|.|..|.:|:|.:|.|..| ||..|:
 Frog   201 AGFCTTGAREKWPVYQTGCMNTLQAFLLNNSITIVGVCIGIALLELFVMTLSMCLCRNL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	72/247 (29%)
		NET-5_like_LEL	110..207	CDD:239418	25/122 (20%)
cd37	NP_001015801.2	Tetraspanin	25..257	CDD:459767	66/231 (29%)
		CD37_CD82_like_LEL	107..232	CDD:239413	25/124 (20%)