Protein Alignment Tsp74F and TSPAN11

DIOPT Version :9

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: XP_011518981.1
• Gene: TSPAN11 / 441631
• HGNCID: 30795
• Length: 302
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 73/227 - (32%)
• Similarity: 120/227 - (52%)
• Gaps: 23/227 - (10%)

  Fly    13 FVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGC 77
            ::||.||:.||..:||||.|..:.:||||::|....:|.::.|:.:.|:|:...:::.:..|||.
Human    15 YLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGFLGF 79

  Fly    78 VGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMA-LYG--SRREITQ 139
            .....|.|..|.|||.::.::|:..|:.|||.:|:.:|:...::|.:..|:| .||  ...:||.
Human    80 GAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQPGATQITA 144

  Fly   140 AWDLTQERLQCCGVDTWHDWNRY----------GPVPESCCQELF--GGQRKECTIFPTITNLY- 191
            :.|..|:..:|||.::..||...          ..||:|||:.:.  .|||..    |  :|:|
Human   145 SVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAH----P--SNIYK 203

  Fly   192 -NQGCLYVTTNFIRDHAAVIGGTSIAVAILMI 222
             ..|||.....|:.||..::|...|.||.|.|
Human   204 VEGGCLTKLEQFLADHLLLMGAVGIGVACLQI 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	73/226 (32%)
TSPAN11	XP_011518981.1	Tetraspannin	16..235	CDD:278750	72/224 (32%)
		PHA03242	<50..>118	CDD:177566	19/67 (28%)
		CD151_like_LEL	112..220	CDD:239408	32/113 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	129	1.000	Domainoid score	I5261
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4638
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48589
OrthoDB	1	1.010	-	-		D1051357at2759
OrthoFinder	1	1.000	-	-		FOG0002118
OrthoInspector	1	1.000	-	-		otm40447
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4418
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.910