DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsp74F and Tspan9

DIOPT Version :9

Sequence 1:	NP_524132.1	Gene:	Tsp74F / 39995	FlyBaseID:	FBgn0036769	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001101360.1	Gene:	Tspan9 / 312728	RGDID:	1304740	Length:	330	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	70/235 - (29%)
Similarity:	121/235 - (51%)	Gaps:	19/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 CCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDR-SFVNELLGTNLFSGAVYVLLVTSIIICLV 72
            ||   :||.:|:.|.:.::.|..:..:.:|..|.: :|..........|.|..|:.:.:|:: :.
  Rat    98 CC---LKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVM-VT 158

  Fly    73 SFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSRREI 137
            .||||:||.||.|||||::||::.::.:..||..:|.:|:.::|.:..:|:::..:.||.:...:
  Rat   159 GFLGCLGAIKENKCLLLSFFIVLLIILLAELILLILFFVYMDKVNENAKQDLKEGLLLYNTENNV 223

  Fly   138 --TQAWDLTQERLQCCGVDTWHDWNRY-----GPVPESCCQELFGGQRKECTIFPTITNLYNQGC 195
              ..||::.|..::||||..:.||  |     ..||:.||.|...|..:..|     |.|:..||
  Rat   224 GLKNAWNIIQAEMRCCGVTDYTDW--YPVLGENTVPDRCCMENSQGCGRNST-----TPLWKTGC 281

  Fly   196 LYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
            ......:..|:..|:|...:...|:.|.||.||..||..|
  Rat   282 YEKVKLWFDDNKHVLGTVGMCFLIMQILGMAFSMTLFQHI 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	65/224 (29%)
Tspan9	NP_001101360.1	Tetraspannin	100..317	CDD:395265	65/224 (29%)
Tspan9	NP_001101360.1	NET-5_like_LEL	196..293	CDD:239418	27/103 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010