DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsp74F and Tspan11

DIOPT Version :9

Sequence 1:	NP_524132.1	Gene:	Tsp74F / 39995	FlyBaseID:	FBgn0036769	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001019433.1	Gene:	Tspan11 / 312727	RGDID:	1305424	Length:	253	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	78/240 - (32%)
Similarity:	125/240 - (52%)	Gaps:	23/240 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGCV 78
            :||.|||.||..:||||.|..:.:||||::|....:|.::.|:.:.|||:....::....|||..
  Rat    16 LKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSVYLSILASSTFAASAYVLIFVGGLVMTTGFLGFG 80

  Fly    79 GAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMA-LYG--SRREITQA 140
            ...:|.|..|.|||.::..:|:..|:.|||.:|:.:|:...:::.:.||:. .||  ...|||.:
  Rat    81 AIIREQKSCLSTYFCLLLAIFLVELVAGVLAHVYYQRLSDELKRHLHSTLTEHYGQPGAAEITAS 145

  Fly   141 WDLTQERLQCCGVDTWHDWNRY----------GPVPESCCQELFG--GQRKECTIFPTITNLY-- 191
            .|..|:..:|||.::..||...          ..||:|||:.:..  |||..    |  :|:|
  Rat   146 VDRLQQDFKCCGSNSSADWQHSVYILSQEAIGRQVPDSCCKTVVARCGQRAH----P--SNIYKV 204

  Fly   192 NQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMIE 236
            ..||:.....|:.||..::|...|.||.|.|.||:.:|.|...::
  Rat   205 EGGCMAKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQ 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	77/233 (33%)
Tspan11	NP_001019433.1	Tetraspannin	16..248	CDD:278750	78/237 (33%)
Tspan11	NP_001019433.1	CD151_like_LEL	112..220	CDD:239408	31/113 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	131	1.000	Domainoid score	I5035
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I4487
OMA	1	1.010	-	-		QHG48589
OrthoDB	1	1.010	-	-		D1051357at2759
OrthoFinder	1	1.000	-	-		FOG0002118
OrthoInspector	1	1.000	-	-		otm44589
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.980