Protein Alignment Tsp74F and Tspan18

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001101220.1
• Gene: Tspan18 / 311210
• RGDID: 1560411
• Length: 248
• Species: Rattus norvegicus
• Alignment Length: 247
• Identity: 71/247 - (28%)
• Similarity: 121/247 - (48%)
• Gaps: 23/247 - (9%)

  Fly    10 CGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTN-LFSGAVYVLLVTSIIICLVS 73
            |...:||.:|:.||.:|:|||.:..:.:|.|||.:...|::.|| |.:...||:|....::.|:.
  Rat     5 CLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYVVLAMGGLLFLLG 69

  Fly    74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERV-QQTMRQEMRSTMALYGSRREI 137
            ||||.||.:|.:||||.:|:.:.::|:..|...:|.::|||.: ::...:|:.............
  Rat    70 FLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTDVF 134

  Fly   138 TQAWDLTQERLQCCGVDTWHDWNRYG----------PVPESCCQ---ELFGG---QRKECTI--F 184
            :..|:.......||||:...|:....          .||::||:   :...|   .|:||.:  .
  Rat   135 SATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGVVLSREECQLGRN 199

  Fly   185 PTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMIE 236
            |.|.   .|||..|..|....:..:.|..:|.|..:.:|.|:|:..||..|:
  Rat   200 PFIN---KQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	68/238 (29%)
		NET-5_like_LEL	110..207	CDD:239418	25/115 (22%)
Tspan18	NP_001101220.1	Tetraspanin	10..245	CDD:459767	68/237 (29%)
		uroplakin_I_like_LEL	105..218	CDD:239409	25/115 (22%)