Protein Alignment Tsp74F and Tspan1

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001004236.1
• Gene: Tspan1 / 298436
• RGDID: 1303308
• Length: 241
• Species: Rattus norvegicus
• Alignment Length: 241
• Identity: 68/241 - (28%)
• Similarity: 116/241 - (48%)
• Gaps: 24/241 - (9%)

  Fly    10 CGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAV------YVLLVTSII 68
            |.:|:|..:.:.|.:||:.||.:..:.:|..||.:...:..| :|.|.|:      |.|:....:
  Rat     3 CFKFIKVMMILFNLLIFLCGAALLAVGIWVSVDGTSFLKAFG-SLSSSAMQFVNVGYFLIAAGAV 66

  Fly    69 ICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMAL--- 130
            :.::.||||.||..|.||:|:.:|.|:.::|:..:.|.|:..|:     .||.::..:.:.:
  Rat    67 LFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVY-----TTMAEQFLTFLVVPAI 126

  Fly   131 ---YGSRREITQAWDLTQERLQCCGVDTWHDWNRYGPVPES------CCQELFGGQRKECTIFPT 186
               ||.:.|.||.|:.|.|.|.|||.:.:.|:|....|.|:      ||.........|......
  Rat   127 EKDYGYQTEFTQVWNSTMEGLHCCGFNNYTDFNSSRFVKENKVFPPFCCANNTDSHTVEPCTEDK 191

  Fly   187 ITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLF 232
            ..::..|||.......||.:|..:||.::.||.|.:..|:.|..|:
  Rat   192 AKSMNVQGCFKQILQKIRTNAVTVGGVAVGVAALELAAMVVSMYLY 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	66/237 (28%)
		NET-5_like_LEL	110..207	CDD:239418	27/108 (25%)
Tspan1	NP_001004236.1	Tetraspanin	7..>151	CDD:459767	43/149 (29%)
		uroplakin_I_like_LEL	106..211	CDD:239409	27/109 (25%)