DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp74F and Cd63

DIOPT Version :9

Sequence 1:	NP_524132.1	Gene:	Tsp74F / 39995	FlyBaseID:	FBgn0036769	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	XP_008763246.1	Gene:	Cd63 / 29186	RGDID:	62080	Length:	262	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	64/234 - (27%)
Similarity:	114/234 - (48%)	Gaps:	19/234 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSF 74
            |.:|:.|.|.:| |.....|.|...:.:..::.::..:|....:|..   .|::.....:.||:|
  Rat    33 CVKFLLYVLLLA-FCACAVGLIAIGVAVQVVLKQAITHETTAGSLLP---VVIIAVGAFLFLVAF 93

  Fly    75 LGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSRREITQ 139
            :||.||.||..||::|:.|.::|:.:..:...:.|||||::|:....:..:..|..|.:..:...
  Rat    94 VGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFSKSFQKQMQNYLTDNKTAT 158

  Fly   140 AWDLTQERLQCCGVDTWHDWNRY-----GPVPESCCQEL---FGGQRKECTIFPTITNLYNQGCL 196
            ..|..|:..:|||...:.||.|.     ..||:|||..:   .|...||.||       :.|||:
  Rat   159 ILDKLQKENKCCGASNYTDWERIPGMAKDRVPDSCCINITVGCGNDFKESTI-------HTQGCV 216

  Fly   197 YVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
            .....::|.:..::.|.::.:|.:.:.|:||||.|...|
  Rat   217 ETIAAWLRKNVLLVAGAALGIAFVEVLGIIFSCCLVKSI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	60/224 (27%)
Cd63	XP_008763246.1	Tetraspannin	33..255	CDD:278750	63/232 (27%)
		ATP-synt_A	<72..131	CDD:294288	18/61 (30%)
		CD63_LEL	129..227	CDD:239419	29/104 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810