Protein Alignment Tsp74F and TSPAN16

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_036598.1
• Gene: TSPAN16 / 26526
• HGNCID: 30725
• Length: 245
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 54/234 - (23%)
• Similarity: 103/234 - (44%)
• Gaps: 35/234 - (14%)

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIII---CLVSFL 75
            :|..|.:.|..:.|.|.|:..|.:......:.:..:||.:    :.|:|.|.::.:   |:...|
Human    11 LKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLGLS----SAYLLHVGNLCLVMGCITVLL 71

  Fly    76 GCV---GAGKEVKCLLLTYFIIVALVF----------VTMLIGGVLGYVFRERVQQTMRQEMRST 127
            ||.   ||.||.:..||  |.|:::|.          |.:|...::|.|..|....|:|:..|.
Human    72 GCAGWYGATKESRGTLL--FCILSMVIVLIMEVTAATVVLLFFPIVGDVALEHTFVTLRKNYRG- 133

  Fly   128 MALYGSRREITQAWDLTQERLQCCGVDTWHDWNRYG-------PVPESCCQELFGGQRKECTIFP 185
               |....:.:..|:|..|:|:||||:.:.|::...       ..|.|||:.:.........:.|
Human   134 ---YNEPDDYSTQWNLVMEKLKCCGVNNYTDFSGSSFEMTTGHTYPRSCCKSIGSVSCDGRDVSP 195

  Fly   186 TITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFG 224
            .:  ::.:||.:......:..:..:.|:|:..|::..:|
Human   196 NV--IHQKGCFHKLLKITKTQSFTLSGSSLGAAVIQRWG 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	54/234 (23%)
		NET-5_like_LEL	110..207	CDD:239418	22/103 (21%)
TSPAN16	NP_036598.1	Tetraspanin	19..>155	CDD:459767	37/145 (26%)
		uroplakin_I_like_LEL	120..215	CDD:239409	21/100 (21%)