Protein Alignment Tsp74F and TSPAN17

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 65/284 - (22%)
• Similarity: 117/284 - (41%)
• Gaps: 69/284 - (24%)

  Fly     9 CCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSG--AVYVLLVTSIIICL 71
            |||   ||.||..|.|.:|.||:...:.||...::..::.:.......|  .|::.:|...::.:
Human    15 CCG---KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSV 76

  Fly    72 VSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSRRE 136
            :.|.||:||.:|...||..:.:.:.|:|...|..|:|.:||::.::..:...:.:.:..|....:
Human    77 LGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDID 141

  Fly   137 ITQAWDLTQERLQCCGVDTWHDWN---------------RYGPVPESCC-----QELFGGQ---- 177
            :....|..||...|||....:|||               |.| ||.|||     :::...|
Human   142 LQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCG-VPFSCCVRDPAEDVLNTQCGYD 205

  Fly   178 -----RKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVA------------------- 218
                 ..|...|     ::.:||:.....:::|:..|:.|..:.:|
Human   206 VRLKLELEQQGF-----IHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQVPLWPHVPLPLPGPPS 265

  Fly   219 -------ILMIFGMIFSCLLFNMI 235
                   :|.|||:   ||..|::
Human   266 LSPHLSSVLQIFGI---CLAQNLV 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	61/275 (22%)
		NET-5_like_LEL	110..207	CDD:239418	25/125 (20%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	34/138 (25%)
		TM4SF9_like_LEL	115..235	CDD:239412	25/125 (20%)