Protein Alignment Tsp74F and Prph2

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_037153.1
• Gene: Prph2 / 25534
• RGDID: 3549
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 49/279 - (17%)
• Similarity: 96/279 - (34%)
• Gaps: 96/279 - (34%)

  Fly    18 LFIANFVIFVGGAIVFCLTLWTLVD---RSFV----------NELLGTNLFSGAVYVLLVTSIII 69
            |::.|::..:.|.::|.|.|:..::   ||.|          |.|:|..:.|
  Rat    20 LWLMNWLSVLAGIVLFSLGLFLKIELRKRSDVMDNSESHFVPNSLIGVGVLS------------- 71

  Fly    70 CLVSFLGCVGAGK------------EVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQ 122
            |:.:.|    |||            :.|..|..|..:.....|.:.:..:..::.|..::.|:..
  Rat    72 CVFNSL----AGKICYDALDPAKYAKWKPWLKLYLAVCVFFNVILFLVALCCFLLRGSLESTLAY 132

  Fly   123 EMRSTMALY-----GSRREITQAWDLTQERLQCCGVDTWHDW-------NRY------------- 162
            .:::.|..|     ..|..:.:..|:.|...:|||.:.:.||       |||
  Rat   133 GLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIK 197

  Fly   163 ---------GPVPESCCQELFGGQRKECTIFPTIT--------------NLYNQGCLYVTTNFIR 204
                     ..||.|||..   ...:.|..:....              ||:.:||.....|:
  Rat   198 SNVDGRYLVDGVPFSCCNP---SSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNY-- 257

  Fly   205 DHAAVIGGTSIAVAILMIF 223
             :::::....:...::.:|
  Rat   258 -YSSLMNSMGVVTLLIWLF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	49/279 (18%)
		NET-5_like_LEL	110..207	CDD:239418	26/144 (18%)
Prph2	NP_037153.1	Tetraspanin	16..181	CDD:459767	34/177 (19%)
		peripherin_like_LEL	120..262	CDD:239415	26/147 (18%)
		Interaction with MREG. /evidence=ECO:0000250	341..346