Protein Alignment Tsp74F and TSPAN15

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 58/259 - (22%)
• Similarity: 117/259 - (45%)
• Gaps: 26/259 - (10%)

  Fly     2 GFSSRMDCCGQF----VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVL 62
            |.|.::..|.:|    :|:||.|.:.|.::.||:|..:.::..|:|.....|  .:.|.....:|
Human     4 GDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIIL 66

  Fly    63 LVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRST 127
            ::..:::.:|||:|.:.:.::...||..:..|:.:..:..|||||:...||.:....:...:|..
Human    67 ILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRG 131

  Fly   128 MALYGSRREITQAWDLTQERLQCCGVDTWHDW--NRY------GP----VPESCC--------QE 172
            :..|....:.....|..|::.:|||.:.:.||  |:|      ||    ||.:||        ..
Human   132 IENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNT 196

  Fly   173 LFGGQRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMIE 236
            :.|.:..:...|.....:|.:||......:..|:..::.|..:.:.:....|::.:.|....:|
Human   197 MCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	53/238 (22%)
		NET-5_like_LEL	110..207	CDD:239418	25/116 (22%)
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	33/138 (24%)
		penumbra_like_LEL	114..231	CDD:239411	25/116 (22%)