DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp74F and TSPAN12

DIOPT Version :9

Sequence 1:NP_524132.1 Gene:Tsp74F / 39995 FlyBaseID:FBgn0036769 Length:236 Species:Drosophila melanogaster
Sequence 2:NP_036470.1 Gene:TSPAN12 / 23554 HGNCID:21641 Length:305 Species:Homo sapiens


Alignment Length:235 Identity:60/235 - (25%)
Similarity:98/235 - (41%) Gaps:25/235 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 LFIANFVIFVGGAIVFCLTLW---------TLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVS 73
            |:..|.:.::....|..::.|         ||...:.|.|.:....|.....|::.....:.:|.
Human    14 LYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVG 78

  Fly    74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRER-----VQQTMRQEMRSTMALYG- 132
            .||..|..|....||..||..:.::|...|..||..|   |:     ||.:....:::.|..|| 
Human    79 MLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTY---EQELMVPVQWSDMVTLKARMTNYGL 140

  Fly   133 -SRREITQAWDLTQERLQCCGVDTWHDWNRYGPV---PESCCQELFGGQRKECTIFPTITNLYNQ 193
             ..|.:|.||:..|...:||||..:.||.....:   |:|||...|.|..|:.. ...:::||.:
Human   141 PRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPGCSKQAH-QEDLSDLYQE 204

  Fly   194 GCLYVTTNFIR--DHAAVIGGTSIAVAILMIFGMIFSCLL 231
            ||.....:|:|  ....|:....|::.:..|..||.:..|
Human   205 GCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp74FNP_524132.1 Tetraspannin 14..231 CDD:395265 59/233 (25%)
TSPAN12NP_036470.1 Tetraspannin 10..244 CDD:395265 59/233 (25%)
TM4SF12_like_LEL 116..218 CDD:239410 30/102 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19282
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

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