Protein Alignment Tsp74F and TSPAN12

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_036470.1
• Gene: TSPAN12 / 23554
• HGNCID: 21641
• Length: 305
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 60/235 - (25%)
• Similarity: 98/235 - (41%)
• Gaps: 25/235 - (10%)

  Fly    18 LFIANFVIFVGGAIVFCLTLW---------TLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVS 73
            |:..|.:.::....|..::.|         ||...:.|.|.:....|.....|::.....:.:|.
Human    14 LYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVG 78

  Fly    74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRER-----VQQTMRQEMRSTMALYG- 132
            .||..|..|....||..||..:.::|...|..||..|   |:     ||.:....:::.|..||
Human    79 MLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTY---EQELMVPVQWSDMVTLKARMTNYGL 140

  Fly   133 -SRREITQAWDLTQERLQCCGVDTWHDWNRYGPV---PESCCQELFGGQRKECTIFPTITNLYNQ 193
             ..|.:|.||:..|...:||||..:.||.....:   |:|||...|.|..|:.. ...:::||.:
Human   141 PRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPGCSKQAH-QEDLSDLYQE 204

  Fly   194 GCLYVTTNFIR--DHAAVIGGTSIAVAILMIFGMIFSCLL 231
            ||.....:|:|  ....|:....|::.:..|..||.:..|
Human   205 GCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	60/235 (26%)
		NET-5_like_LEL	110..207	CDD:239418	31/108 (29%)
TSPAN12	NP_036470.1	Tetraspanin	10..246	CDD:459767	60/235 (26%)
		TM4SF12_like_LEL	116..218	CDD:239410	30/102 (29%)