Protein Alignment Tsp74F and Tspan8

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_666122.1
• Gene: Tspan8 / 216350
• MGIID: 2384918
• Length: 235
• Species: Mus musculus
• Alignment Length: 237
• Identity: 64/237 - (27%)
• Similarity: 116/237 - (48%)
• Gaps: 27/237 - (11%)

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELL-----GTNLFSGAVYVLLVTSIIICLVS 73
            :|||:|..||:.:|.|.::..|.:|..|.:. ..|::     .||.|. ||.:|:....||.::.
Mouse     8 LKYSMFFFNFLFWVCGTLILGLAIWVRVSKD-GKEIITSGDSSTNPFI-AVNILIAVGSIIMVLG 70

  Fly    74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSR---- 134
            ||||.||.||.:|:||.:||.:.|:.:..:..|:||..|:....:.:.:.:.....|....
Mouse    71 FLGCCGAVKESRCMLLLFFIGLLLILILQVAAGILGAAFKPEYNRILNETLYENAKLLSDNTDEA 135

  Fly   135 REITQAWDLTQERLQCCGVDTW-HDW-NRYGPVPESCCQELFGGQRKECTIFPTIT----NLYNQ 193
            ::..:|..:.|...:|||::.. .|| |.:....|||          :||.....|    ::|.:
Mouse   136 KDFQKAMIVFQSEFKCCGLENGAADWGNNFVEAKESC----------QCTGTDCATYQGSSVYPK 190

  Fly   194 GCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
            .||.:..:....:..::.|.:..:|::.|.|::||.:|:..|
Mouse   191 TCLSLIKDLFEKNIIIVIGIAFGLAVIEILGLVFSMVLYCQI 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	63/233 (27%)
		NET-5_like_LEL	110..207	CDD:239418	19/106 (18%)
Tspan8	NP_666122.1	Tetraspanin	8..230	CDD:459767	63/233 (27%)
		TM4SF3_like_LEL	106..204	CDD:239407	20/107 (19%)