Protein Alignment Tsp74F and tsp-17

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001129920.2
• Gene: tsp-17 / 192067
• WormBaseID: WBGene00006643
• Length: 312
• Species: Caenorhabditis elegans
• Alignment Length: 305
• Identity: 58/305 - (19%)
• Similarity: 102/305 - (33%)
• Gaps: 98/305 - (32%)

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVD--RSFVNELL----GTNLFSGAVYVLLVTSIIICLV 72
            |..|:|...:.:...|.:.  |.||.|:|  |:::.:|:    ...|...:.||.||......||
 Worm    13 VAVSIFSIYYWLSALGHVF--LGLWMLLDPKRNYILDLVHFSENDPLLKASAYVSLVCGCAQLLV 75

  Fly    73 SFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRER---------------------- 115
            .|||..||....:.|||.:.:.:...|:..:..|.|...::::
 Worm    76 GFLGLCGAVNRSRFLLLAFVMFLIGTFLADVAMGTLSLFYKDKFSNNYMGVYLKNLTYNRYSRDR 140

  Fly   116 ---------------VQQTMRQEMRSTMALYGSRRE---ITQAWDLTQERLQCCGVDTWHDWNRY 162
                           |::.:|:.::|...:..|..|   :|:..|..|...:|||        ..
 Worm   141 WVLPLMDTIQFYVYSVKENVREIVKSKYGVMTSEPENKMVTEFIDKLQFYEKCCG--------SL 197

  Fly   163 GPV-----------------------PESCCQELFGGQRKECTIFPTITNLYNQ----------- 193
            ||.                       |.|||.::.|     .:....:...|.:
 Worm   198 GPTDYISSRWSQSTNQDSEEIESPLFPVSCCTQITG-----ASALNPLAKSYARCQQIGANRQWR 257

  Fly   194 ---GCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
               ||.....::..:...:..|.....|:.|:.|:..||.|.:.|
 Worm   258 HAVGCSERLMSWFNEQIWIFVGFGFGSALTMMLGICLSCCLISKI 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	57/301 (19%)
		NET-5_like_LEL	110..207	CDD:239418	21/173 (12%)
tsp-17	NP_001129920.2	Tetraspanin	11..>150	CDD:459767	29/138 (21%)
		CD37_CD82_like_LEL	153..275	CDD:239413	21/134 (16%)