Protein Alignment Tsp74F and Prph2

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_032964.1
• Gene: Prph2 / 19133
• MGIID: 102791
• Length: 346
• Species: Mus musculus
• Alignment Length: 266
• Identity: 44/266 - (16%)
• Similarity: 96/266 - (36%)
• Gaps: 70/266 - (26%)

  Fly    18 LFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGCVGAGK 82
            |::.|::..:.|.::|.|.|:..::....:|::..:........|:...::.|:.:.|    |||
Mouse    20 LWLMNWLSVLAGIVLFSLGLFLKIELRKRSEVMNNSESHFVPNSLIGVGVLSCVFNSL----AGK 80

  Fly    83 ------------EVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALY---- 131
                        :.|..|..|..:.....|.:.:..:..::.|..::.|:...:::.|..|
Mouse    81 ICYDALDPAKYAKWKPWLKPYLAVCIFFNVILFLVALCCFLLRGSLESTLAYGLKNGMKYYRDTD 145

  Fly   132 -GSRREITQAWDLTQERLQCCGVDTWHDW-------NRY----------------------GPVP 166
             ..|..:.:..|:.|...:|||.:.:.||       |||                      ..||
Mouse   146 TPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVP 210

  Fly   167 ESCCQELFGGQRKECTIFPTIT--------------NLYNQGCLYVTTNFIRDHAAVIGGTSIAV 217
            .|||..   ...:.|..:....              ||:.:||.....|:   :::::....:..
Mouse   211 FSCCNP---SSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNY---YSSLMNSMGVVT 269

  Fly   218 AILMIF 223
            .::.:|
Mouse   270 LLVWLF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	44/266 (17%)
		NET-5_like_LEL	110..207	CDD:239418	26/144 (18%)
Prph2	NP_032964.1	Tetraspanin	16..181	CDD:459767	29/164 (18%)
		peripherin_like_LEL	120..262	CDD:239415	26/147 (18%)
		Interaction with MREG. /evidence=ECO:0000269|PubMed:17260955	341..346