Protein Alignment Tsp74F and tsp-14

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_001367834.1
• Gene: tsp-14 / 180761
• WormBaseID: WBGene00006640
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 282
• Identity: 63/282 - (22%)
• Similarity: 108/282 - (38%)
• Gaps: 85/282 - (30%)

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTSIIICLVSFLGCV 78
            :|:.:|:.|.::|:.|..:..|.::..: :.| .|:...::......::.:....||:|||.|.:
 Worm    54 LKWLVFLLNSIVFLVGVGILALGVYLFI-KDF-REVKLVDIILNPAILISIFGFSICVVSFFGFM 116

  Fly    79 GAGKE--------VKCLLLTYFIIVA--LVFVTML---------IGGVLGYVFRERVQQTMRQEM 124
            ||.::        ..|:.|:|.::||  |||.|:.         ...:|.|..:.
 Worm   117 GALRDNIFLLKCFAACVFLSYILVVAVTLVFFTLFYTDTTEGLSANWLLLYAVKN---------- 171

  Fly   125 RSTMALYGSRREITQAWDLTQERLQCCGVDT----WHDWN--------RYGPVPE------SCCQ 171
                  |.:.|.:.:..|..||.|:||||.:    :.|||        ...|.||      |||:
 Worm   172 ------YHTNRNLAEIMDALQENLECCGVSSIAQGYRDWNMSYQFNCTNSNPQPEKCGVPFSCCR 230

  Fly   172 -----ELFGGQRKECTIFPTITNL------------------YNQGCLYVTTNFIRDHAAVIGGT 213
                 |..|...   .:.|.:.:|                  |.:|||.........||..:|
 Worm   231 KSVISEAAGSSN---PLLPAMRSLECWQNALTKRPGDLEHDIYTRGCLQPLRTLFESHAVHVG-- 290

  Fly   214 SIAVAILMIFGMIFSCLLFNMI 235
              |...|:|..:..|..|.|::
 Worm   291 --AFVALLIVPVCISVCLTNIL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	62/278 (22%)
		NET-5_like_LEL	110..207	CDD:239418	28/137 (20%)
tsp-14	NP_001367834.1	Tetraspanin	54..>193	CDD:459767	34/156 (22%)
		tetraspanin_LEL	145..286	CDD:351888	33/159 (21%)