Protein Alignment Tsp74F and tsp-12

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_501853.1
• Gene: tsp-12 / 177890
• WormBaseID: WBGene00006638
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 269
• Identity: 62/269 - (23%)
• Similarity: 114/269 - (42%)
• Gaps: 49/269 - (18%)

  Fly     2 GFSSRMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDR-SFVNEL-LGTNLFSGAVYVLLV 64
            |..|.:.||   ||||:|..|.:.|:.|..:....:|..::: :|||.| ..:.|:....:.||:
 Worm    29 GGESEISCC---VKYSVFSFNVIFFLLGFGLLLFGVWAQIEKNTFVNMLSKASKLYLDPTWPLLI 90

  Fly    65 TSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMA 129
            ...:..::.|.||||:.:|....|..|..::.|:.:.....||..|..|:::...:|..:...:.
 Worm    91 VGFLTFIIGFSGCVGSLRENTSFLTFYSTLLGLLLIAEFSAGVFAYACRDQLDNYIRNLLNDVVV 155

  Fly   130 LYGSRREITQAWDLTQERLQCCGVDTWHDWNR---------------YGPVPESCC--------Q 171
            .|....::....|..||...|||::...||:|               .|.||.|||        :
 Worm   156 GYRDDPDLQLLIDSMQETWMCCGINGADDWDRNTYFSIEAREVASPEAGGVPFSCCINSSKLEFK 220

  Fly   172 ELFGG-----------------QRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAI 219
            ..|.|                 ||    :.....::|.:|||.....::.::..::..:.:.:||
 Worm   221 NYFCGHGVRLKPESHMAAHLAAQR----VMAHTASIYTEGCLPKLQLWLNNNMLLVAVSMVIIAI 281

  Fly   220 LMIFGMIFS 228
            :.:.|:.|:
 Worm   282 IQVLGICFA 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	58/257 (23%)
		NET-5_like_LEL	110..207	CDD:239418	27/136 (20%)
tsp-12	NP_501853.1	Tetraspanin	38..293	CDD:459767	58/257 (23%)
		tetraspanin_LEL	133..268	CDD:351888	28/138 (20%)