Protein Alignment Tsp74F and Tspan8

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 238
• Identity: 65/238 - (27%)
• Similarity: 116/238 - (48%)
• Gaps: 29/238 - (12%)

  Fly    14 VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELL-----GTNLFSGAVYVLLVTSIIICLVS 73
            :|||:|..||:.:|.|.::..|.:|..|.:. ..|::     |||.|. ||.:|:....||.::.
  Rat     8 LKYSMFFFNFLFWVCGTLILGLAIWLRVSKD-GKEIITSGDNGTNPFI-AVNILIAVGSIIMVLG 70

  Fly    74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRER----VQQTMRQEMRSTMALYGSR 134
            ||||.||.||.:|:||.:||.:.|:.:..:..|:||..|:..    :.:|:.:..:.........
  Rat    71 FLGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGATFKSESSRILNETLYENAKLLSETSNEA 135

  Fly   135 REITQAWDLTQERLQCCGVDTW-HDWNRYGPVPESCCQ------ELFGGQRKECTIFPTITNLYN 192
            :|:.:|....|...:|||:... .||.:..|..:..||      |.:.|:           |:|.
  Rat   136 KEVQKAMIAFQSEFKCCGLRFGAADWGKNFPDAKESCQCTGSDCESYNGE-----------NVYR 189

  Fly   193 QGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
            ..||.:....:..:..::.|.:..:|::.|.|::||.:|:..|
  Rat   190 TTCLSLIKELVEKNIIIVIGIAFGLAVIEILGLVFSMVLYCQI 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	64/234 (27%)
		NET-5_like_LEL	110..207	CDD:239418	19/107 (18%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	64/234 (27%)
		TM4SF3_like_LEL	106..204	CDD:239407	20/108 (19%)