Protein Alignment Tsp74F and UPK1A

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 53/238 - (22%)
• Similarity: 92/238 - (38%)
• Gaps: 49/238 - (20%)

  Fly    18 LFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGT----NLFSGAVYVLLVTSIIICLVSFLGCV 78
            |.:.|.:|.:.|..:|..|:|...|:..|..|:|.    ::|:|| ::.:.......:|:..|..
Human    21 LVVGNIIILLSGLSLFAETIWVTADQYRVYPLMGVSGKDDVFAGA-WIAIFCGFSFFMVASFGVG 84

  Fly    79 GAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGS----RREITQ 139
            .|....:.::|||.:::.:|::......:..|..|:.:........:..:..|.:    .:|:|:
Human    85 AALCRRRSMVLTYLVLMLIVYIFECASCITSYTHRDYMVSNPSLITKQMLTFYSADTDQGQELTR 149

  Fly   140 AWDLTQERLQCCGVDTWHDWNRYG------------PVPESCCQELFGGQRKECTIFPTITNLYN 192
            .||......:|||.....||..:.            |.|..||       |:.....|    |..
Human   150 LWDRVMIEQECCGTSGPMDWVNFTSAFRAATPEVVFPWPPLCC-------RRTGNFIP----LNE 203

  Fly   193 QGCL-----YVTTNFIRDHAAVIG--------GTS-IAVAILM 221
            :||.     |:.|....:|   ||        |.| ...||||
Human   204 EGCRLGHMDYLFTKGCFEH---IGHAIDSYTWGISWFGFAILM 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	53/238 (22%)
		NET-5_like_LEL	110..207	CDD:239418	23/117 (20%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	29/138 (21%)
		uroplakin_I_like_LEL	113..231	CDD:239409	26/131 (20%)