Protein Alignment Tsp74F and TSPAN2

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 61/249 - (24%)
• Similarity: 98/249 - (39%)
• Gaps: 57/249 - (22%)

  Fly     1 MG-FSSRMDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVD---RSFVNELLGTNLFSGAVYV 61
            || |...:.|    :||.|...|.:.::.|:.|....||....   :...:|......|...:||
Human     1 MGRFRGGLRC----IKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYV 61

  Fly    62 LLVTSIIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRE---RVQQTMRQE 123
            |:....::..|.|.||.||.:|.:|:|.::|..:.::|...:..||..::.:.   |..|||.:|
Human    62 LVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEE 126

  Fly   124 M-----------RSTMALYGSRREITQAWDLTQERLQCCGVDTWHDWNRYGPVPESCCQELFGGQ 177
            .           ..|:..:.|             ..||||.::...      |..:|.:||.|
Human   127 AYNDYLKDRGKGNGTLITFHS-------------TFQCCGKESSEQ------VQPTCPKELLG-- 170

  Fly   178 RKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLL 231
                          ::.|:......|.....:||...|.:|.|.|||||||.:|
Human   171 --------------HKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVL 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	57/235 (24%)
		NET-5_like_LEL	110..207	CDD:239418	18/110 (16%)
TSPAN2	NP_005716.2	Tetraspanin	11..212	CDD:459767	57/235 (24%)
		CD81_like_LEL	110..186	CDD:239404	18/110 (16%)