Protein Alignment Tsp74F and TSPAN3

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 62/250 - (24%)
• Similarity: 110/250 - (44%)
• Gaps: 42/250 - (16%)

  Fly     7 MDCCGQFVKYSLFIANFVIFVGGAIVFC------LTLWTLVDRSFVNELLGTNLFSGAVYVLLVT 65
            |..||.....::.:...:||.|.|.:.|      ...:...|..|.:           ||.|:..
Human     1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFED-----------VYTLIPA 54

  Fly    66 SIIIC------LVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEM 124
            .:||.      ::..:||....:|.:|.|.|:.||:.|||||.::..|||||:|.:|:..:.:.:
Human    55 VVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119

  Fly   125 RSTMALYGSRR--EITQAWDLTQERLQCCGVDTWHDW--------NRYGPVPESCCQELFGGQRK 179
            :.....|....  ..::|.|..|.:|.|||:..:.||        .:...||.|||:|    ...
Human   120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRE----TAS 180

  Fly   180 ECT---IFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLL 231
            .|.   ..|  ::||.:||..:....:::....:...::|.|.:.:.||:.:|::
Human   181 NCNGSLAHP--SDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIV 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	59/242 (24%)
		NET-5_like_LEL	110..207	CDD:239418	26/109 (24%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	59/241 (24%)
		TM4SF8_like_LEL	104..210	CDD:239416	27/111 (24%)