Protein Alignment Tsp74F and TSPAN5

DIOPT Version :10

• Sequence 1: NP_524132.1
• Gene: Tsp74F / 39995
• FlyBaseID: FBgn0036769
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 64/256 - (25%)
• Similarity: 119/256 - (46%)
• Gaps: 35/256 - (13%)

  Fly     7 MDCCGQFVKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSG--AVYVLLVTSIII 69
            :.||   :||.:|..|.:.:..|.....:.||...::..::.:.......|  .|::.||...::
Human    11 VSCC---IKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVM 72

  Fly    70 CLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSR 134
            .::.|.||:||.:|...||..:.:.:.::|...|..|||.:||::.::..:...:.:.:..|...
Human    73 FILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRAYRDD 137

  Fly   135 REITQAWDLTQERLQCCGVDTWHDWN---------------RYGPVPESCC-----QELFGGQ-- 177
            .::....|.|||..||||.....|||               |.| ||.|||     :::...|
Human   138 IDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCG-VPFSCCTKDPAEDVINTQCG 201

  Fly   178 ---RKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMI 235
               |::..:...|. :|.:||:.....:::|:..::.|..|.:|:|.|||:   ||..|::
Human   202 YDARQKPEVDQQIV-IYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGI---CLAQNLV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspanin	14..233	CDD:459767	61/245 (25%)
		NET-5_like_LEL	110..207	CDD:239418	28/121 (23%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	62/247 (25%)
		TM4SF9_like_LEL	113..233	CDD:239412	28/121 (23%)