DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp74F and cd151

DIOPT Version :9

Sequence 1:	NP_524132.1	Gene:	Tsp74F / 39995	FlyBaseID:	FBgn0036769	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	XP_031755690.1	Gene:	cd151 / 100144686	XenbaseID:	XB-GENE-480009	Length:	266	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	75/258 - (29%)
Similarity:	131/258 - (50%)	Gaps:	29/258 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FSSRMDCCGQF-VKYSLFIANFVIFVGGAIVFCLTLWTLVDRSFVNELLGTNLFSGAVYVLLVTS 66
            ::.:.:.||.. :||.||..||..::.|..|..:.:|||:.:|....||.:|.::...|:|::..
Frog    10 YNEKKETCGTICLKYLLFTFNFFFWLAGLAVMAVGIWTLIQKSDYISLLPSNTYAATAYILVIAG 74

  Fly    67 IIICLVSFLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRER-----------VQQTM 120
            .|:.:...|||....||.|.||..|||::..:|:..::.|:|.|::.::           ::|::
Frog    75 AIVMITGILGCCATFKERKSLLKVYFILLLCIFILEVLAGILAYIYYQQCTPFCLQLNAELKQSL 139

  Fly   121 RQEMRSTMALYGSRREITQAWDLTQERLQCCGVDTWHDWNR----YGP------VPESCCQELFG 175
            :|.|.:.....|..: :|.|.|..|:..:|||.:...||..    ..|      ||:|||:.:
Frog   140 KQTMTTKYKQPGEEK-VTNAVDKLQQEFKCCGSNNSEDWRDSIWINSPEAEKRLVPDSCCKTV-- 201

  Fly   176 GQRKECTIFPTITNLYNQ--GCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMIFSCLLFNMIE 236
              .:.|.|....:|:|..  ||:.....|||.|..:||...|.:|.:.:|||||:|.|:..::
Frog   202 --TQRCGIRDHPSNIYKTEGGCITKLETFIRAHLLIIGAVGIGIACVQLFGMIFTCCLYRSLK 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp74F	NP_524132.1	Tetraspannin	14..231	CDD:395265	72/239 (30%)
cd151	XP_031755690.1	Tetraspannin	22..257	CDD:395265	72/239 (30%)
cd151	XP_031755690.1	CD151_like_LEL	118..233	CDD:239408	29/119 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5013
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20916
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4439
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1051357at2759
OrthoFinder	1	1.000	-	-		FOG0002118
OrthoInspector	1	1.000	-	-		otm47627
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4418
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090