DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7402 and galns

DIOPT Version :9

Sequence 1:	NP_649023.1	Gene:	CG7402 / 39994	FlyBaseID:	FBgn0036768	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001074110.2	Gene:	galns / 791159	ZFINID:	ZDB-GENE-070112-1152	Length:	514	Species:	Danio rerio

Alignment Length:	549	Identity:	154/549 - (28%)
Similarity:	230/549 - (41%)	Gaps:	107/549 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVLLVVSSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYV 71
            :.|..|..:|...|....|..|||:|:|:||||..|:...|.....||.:|.:|..|:|....|.
Zfish     1 MCLQAVICVLWTVYVCQTSGSPNIIIMLMDDMGWGDLGVFGEPSKETPYLDLMAAQGMLFPNFYT 65

  Fly    72 PN-LCTPSRATLLTGKYPIHTGM-------------QHFVIITDEPWGLPQRERLMPEIFRDAGY 122
            .| ||:||||.||||:.|:..|.             |..|      .|:...|.|:||:.::..|
Zfish    66 ANPLCSPSRAALLTGRLPVRNGFYTTNAHARNAYTPQEIV------GGISADEILLPELLKNKHY 124

  Fly   123 STHLVGKWHLGFWRKDLTPTMRGFDH-------HFGYYNG----YIDYYDHQVRMLDRNYSAGLD 176
            .:.:|||||||. |....|...|||.       |||.||.    .|..|::. .|..|.|.   :
Zfish   125 VSKIVGKWHLGH-RTQYLPLKHGFDEWFGAPNCHFGPYNDSSRPNIPVYNNS-EMKGRYYE---E 184

  Fly   177 FRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKS-KPLFMVLSHLAVHTGNEDSPMQAPEEEVAK 240
            |..::: ..|:|   .|:.:..|....|.|...: :|.|:..:..|.|     :|:.|.:
Zfish   185 FEINVK-TGESN---LTQLYLKEGLDFISQQAMAQRPFFLYWAPDATH-----APVYASK----- 235

  Fly   241 FPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYR 305
             |.:...:|..|...:..||.|:.|.:..|...|:.|::::...|||||..:.....:|||.|:.
Zfish   236 -PFLGKSQRGRYGDAVMELDDSIGQILAHLVSLGIQNDTLVFFTSDNGAALMSGPLQSGSNAPFL 299

  Fly   306 GQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPML 370
            ..||:.:|||:|.....|.|.....|.||:|....:|...|....||||.|.|..:||::|.|:|
Zfish   300 CGKETTFEGGMREPAMAWWPGQIPAGTVSHQLASVMDLFSTSLSVAGVSPPDDRVIDGVDLSPVL 364

  Fly   371 SGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVL 435
            ....         ::|....|  |..:.:..|....:|..|..|...:|.
Zfish   365 FNGS---------LIDRPIFY--YRGNQMMAVRIGQYKAHYWTWSNSMEE--------------- 403

  Fly   436 ASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQN--PLESHFKCEPLKAPCFFDLAKDPCERY 498
                    .|:|:             ..||   ||.  .:.:|.:.|....|..|.|.:||.|||
Zfish   404 --------FNKGI-------------NFCP---GQEVPGVTTHTQQEHTMQPLIFHLGRDPGERY 444

  Fly   499 NLA---QMYPLQLQQLADELEQIRKTAIP 524
            .|:   :.|....:::...:||.:|..||
Zfish   445 PLSVQCKEYRDVFRRVTAVVEQHQKLLIP 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	129/459 (28%)
CG7402	NP_649023.1	4-S	28..436	CDD:293753	126/433 (29%)
galns	NP_001074110.2	AslA	18..475	CDD:225661	150/532 (28%)
galns	NP_001074110.2	GALNS	22..486	CDD:293776	149/528 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592900
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740